Publications 2019-2020
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Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses
Journal article
Alsaleh G. et al, (2020), eLife, 9
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Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease. An International Multicenter Study
Journal article
Drake TM. et al, (2020), American Journal of Respiratory and Critical Care Medicine, 202, 1656 - 1665
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Efficacy and safety of tenofovir disoproxil fumarate (TDF) in hepatitis B virus (HBV) monoinfection: longitudinal analysis of a UK cohort
Journal article
Wang T. et al, (2020)
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Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report
Journal article
Buckland MS. et al, (2020), Nature Communications, 11
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Whole Blood Profiling of T-cell-Derived microRNA Allows the Development of Prognostic models in Inflammatory Bowel Disease
Conference paper
Kalla R. et al, (2020), Journal of Crohn's and Colitis, 14, 1724 - 1733
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Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison
Journal article
Ainsworth M. et al, (2020), The Lancet Infectious Diseases, 20, 1390 - 1400
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Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
Journal article
Ramasamy MN. et al, (2020), The Lancet, 396, 1979 - 1993
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Crohn's Colitis Care (CCCare): bespoke cloud-based clinical management software for inflammatory bowel disease.
Journal article
Krishnaprasad K. et al, (2020), Scandinavian journal of gastroenterology, 55, 1419 - 1426
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Performance of a high-throughput next-generation sequencing method for analysis of HIV drug resistance and viral load
Journal article
Fogel JM. et al, (2020), Journal of Antimicrobial Chemotherapy, 75, 3510 - 3516
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Epidemiological changes on the Isle of Wight after the launch of the NHS Test and Trace programme: a preliminary analysis
Journal article
Kendall M. et al, (2020), The Lancet Digital Health, 2, e658 - e666
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Demyelination After Anti-TNF Therapy: Who is at Risk?
Journal article
Williams I. and Uhlig HH., (2020), Journal of Crohn's & colitis, 14, 1651 - 1652
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Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis
Journal article
Trzupek D. et al, (2020), Genome Medicine, 12
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A variant in IL6ST with a selective IL-11 signaling defect in human and mouse
Journal article
Schwerd T. et al, (2020), Bone Research, 8
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Mucosal-associated invariant T (MAIT) cells are activated in the gastrointestinal tissue of patients with combination ipilimumab and nivolumab therapy-related colitis in a pathology distinct from ulcerative colitis.
Journal article
Sasson SC. et al, (2020), Clinical and experimental immunology, 202, 335 - 352
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Adenoviral vaccines promote protective tissue-resident memory T cell populations against cancer.
Journal article
van der Gracht ET. et al, (2020), Journal for immunotherapy of cancer, 8
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MAIT Cells in Barrier Tissues: Lessons from Immediate Neighbors
Journal article
Amini A. et al, (2020), Frontiers in Immunology, 11
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Liver cT1 decreases following direct-acting antiviral therapy in patients with chronic hepatitis C virus.
Journal article
Jayaswal ANA. et al, (2020), Abdominal radiology (New York)
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Expression of type I interferon-associated genes at point of antiretroviral therapy interruption predicts time to HIV virological rebound
Preprint
Zacharapoulou P. et al, (2020)
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Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia
Journal article
Moreira LM. et al, (2020), Nature, 587, 460 - 465
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Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial.
Journal article
Brenner A. et al, (2020), Critical care (London, England), 24
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Establishing key research questions for the implementation of artificial intelligence in colonoscopy - a modified Delphi method.
Journal article
Ahmad OF. et al, (2020), Endoscopy
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The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity
Preprint
Thomson EC. et al, (2020)
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Author Correction: Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models
Journal article
Liu PJ. et al, (2020), Scientific Reports, 10
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Outcomes following SARS-CoV-2 infection in liver transplant recipients: an international registry study
Journal article
Webb GJ. et al, (2020), The Lancet Gastroenterology & Hepatology, 5, 1008 - 1016
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ECCO Position Paper: Harmonization of the Approach to Ulcerative Colitis Histopathology.
Journal article
Magro F. et al, (2020), Journal of Crohn's & colitis, 14, 1503 - 1511
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National Institute for Health Research Health Informatics Collaborative: development of a pipeline to collate electronic clinical data for viral hepatitis research.
Journal article
Smith DA. et al, (2020), BMJ health & care informatics, 27
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Prevalence and long-term outcome of sub-clinical primary sclerosing cholangitis in patients with ulcerative colitis.
Journal article
Culver EL. et al, (2020), Liver international : official journal of the International Association for the Study of the Liver, 40, 2744 - 2757
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AMAP RISK SCORE PREDICTS HEPATOCELLULAR CARCINOMA DEVELOPMENT IN CHRONIC HEPATITIS PATIENTS: AN INTERNATIONAL COHORT COLLABORATION
Conference paper
Fan R. et al, (2020), HEPATOLOGY, 72, 97A - 98A
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The battle for iron in enteric infections.
Journal article
Sousa Gerós A. et al, (2020), Immunology, 161, 186 - 199
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Characterizing Hepatitis C Virus-Specific CD4+ T Cells Following Viral-Vectored Vaccination, Directly Acting Antivirals, and Spontaneous Viral Cure.
Journal article
Hartnell F. et al, (2020), Hepatology (Baltimore, Md.), 72, 1541 - 1555
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Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Journal article
Peng Y. et al, (2020), Nature Immunology, 21, 1336 - 1345
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Impact of virus subtype and host IFNL4 genotype on large-scale RNA structure formation in the genome of hepatitis C virus
Journal article
Simmonds P. et al, (2020), RNA, 26, 1541 - 1556
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SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020
Journal article
Lumley SF. et al, (2020), Eurosurveillance, 25
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Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020
Working paper
Thompson CP. et al, (2020), Eurosurveillance, 25
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Homologous and heterologous re-challenge with Salmonella Typhi and Salmonella Paratyphi A in a randomised controlled human infection model.
Journal article
Gibani MM. et al, (2020), PLoS neglected tropical diseases, 14
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Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge
Journal article
Raman B. et al, (2020)
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Bimodal distribution and set point HBV DNA viral loads in chronic infection: retrospective analysis of cohorts from the UK and South Africa
Journal article
Downs LO. et al, (2020), Wellcome Open Research, 5, 113 - 113
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Case Report: Application of hepatitis B virus (HBV) deep sequencing to distinguish between acute and chronic infection
Journal article
Downs LO. et al, (2020), Wellcome Open Research, 5, 240 - 240
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A haemagglutination test for rapid detection of antibodies to SARS-CoV-2
Preprint
Joly E. et al, (2020)
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Mapping of HIV-1C Transmission Networks Reveals Extensive Spread of Viral Lineages Across Villages in Botswana Treatment-as-Prevention Trial
Journal article
Novitsky V. et al, (2020), The Journal of Infectious Diseases, 222, 1670 - 1680
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Optimising T cell (re)boosting strategies for adenoviral and modified vaccinia Ankara vaccine regimens in humans.
Journal article
Capone S. et al, (2020), NPJ vaccines, 5
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SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus
Journal article
Andersson MI. et al, (2020), Wellcome Open Research, 5, 181 - 181
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Presumed Risk Factors and Biomarkers for Severe Respiratory Syncytial Virus Disease and Related Sequelae: Protocol for an Observational Multicenter, Case-Control Study From the Respiratory Syncytial Virus Consortium in Europe (RESCEU)
Journal article
Jefferies K. et al, (2020), The Journal of Infectious Diseases, 222, S658 - S665
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Simultaneous Viral Whole-Genome Sequencing and Differential Expression Profiling in Respiratory Syncytial Virus Infection of Infants
Journal article
Lin G-L. et al, (2020), The Journal of Infectious Diseases, 222, S666 - S671
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Artificial intelligence-driven real-time 3D surface quantification of Barrett’s oesophagus for risk stratification and therapeutic response monitoring
Working paper
Ali S. et al, (2020)
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A haemagglutination test for rapid detection of antibodies to SARS-CoV-2
Journal article
Townsend A. et al, (2020)
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Lymphocyte Activation Gene (LAG)-3 Is Associated With Mucosal Inflammation and Disease Activity in Ulcerative Colitis
Journal article
Slevin SM. et al, (2020), Journal of Crohn's and Colitis, 14, 1446 - 1461
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Faecal microbiota signatures of IBD and their relation to diagnosis, disease phenotype, inflammation, treatment escalation and anti-TNF response in a European Multicentre Study (IBD-Character)
Journal article
Vatn S. et al, (2020), Scandinavian Journal of Gastroenterology, 55, 1146 - 1156
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A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals
Journal article
Demetriou P. et al, (2020), Nature Immunology, 21, 1232 - 1243
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Letter: extending FIT from DG30 to NG12 patients. Letter: faecal immunochemical testing for adults with symptoms of colorectal cancer - ready for prime time? Authors' reply: a unified approach to safety netting negative FITs is required
Journal article
Nicholson BD. et al, (2020), ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 52, 1420 - 1421