Modernising Medical Microbiology
Modernising Medical Microbiology is a research group aiming to transform how we analyse and treat infections, to improve patient care.
We aim to:
1) Modernise the way we analyse infections, bringing cutting-edge scientific techniques to clinical care.
2) Transform they way we study the treatment of patients with infections, using large databases of hospital electronic information, to identify trends in how infections are behaving, and ways patient care can be improved.
3) Use techniques such as DNA analysis of bacteria and viruses to better understand how infections spread, how to treat them, and how to prevent them in the future.
4) Study how bacteria become resistant to antibiotics, and more difficult to treat, and how to prevent this.
and how to prevent this.
Modernising Medical Microbiology studies a number of infections, in particular, Mycobacterium tuberculosis (TB), - the Enterobacterales family (Escherichia coli, Klebsiella species and others) and Clostridium difficile (C. diff).
You can learn more about these bacteria here
Projects
The Modernising Medical Microbiology Research Group has many active research projects.
You can learn more about the projects here.
Public Involvement
If you are interested in being a part of our public engagement team, please get in contact!
Pathogens and viruses
What Pathogens and Viruses do the MMM team research?
Latest publications
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Efficacy of ultra-short, response-guided sofosbuvir and daclatasvir therapy for Hepatitis C: a single arm mechanistic pilot study
Journal article
Flower B. et al, (2023), eLife, 12
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Comparison of R9.4.1/Kit10 and R10/Kit12 Oxford Nanopore flowcells and chemistries in bacterial genome reconstruction
Journal article
Sanderson ND. et al, (2023), Microbial Genomics, 9
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Virus Detection and Identification in Minutes Using Single-Particle Imaging and Deep Learning.
Journal article
Shiaelis N. et al, (2022), ACS nano
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Epidemiological cut-off values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing ofM. tuberculosis
Journal article
(2022), European Respiratory Journal, 60, 2200239 - 2200239
Blog posts
COVID-19: accelerating testing with robotics
Kevin Chau, a PhD student on our National PhD Training Programme in AMR Research, has contributed to the pandemic response as part of the Modernising Medical Microbiology team at John Radcliffe Hospital in Oxford. In a new blog post, he describes the experience.
Monitoring Populations at risk from Coronavirus
Emma Pritchard, Statistician and PhD student shares her work with ONS on Coronavirus statistics.