Graduate Studies

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A number of opportunities for postgraduate students exist within Experimental Medicine, to study and undertake research towards a Doctor of Philosophy (D.Phil.) degree. There is also a Master of Science (M.Sc.) course in Integrated Immunology run by the Nuffield Department of Surgery. 


Doctoral Projects

Projects avaliable in Experimental Medicine are listed below. For further information about projects, admissions and funding with the Nuffield Department of Clinical Medicine go to Graduate Studies.


DPhil Project Project Supervisors Theme
A comprehensive computational platform to improve liquid biopsies for cancer detection (reference number 961) Schuster-Böckler, Benjamin and Song, Chunxiao
AhR(port) dynamics: mapping the AhR connections and their roles in immunity to infection. (reference number 1063) Moura Alves, Pedro and Gyrd-Hansen, Mads
An integrated understanding of HIV transmission (reference number 1013) Lythgoe, Dr Katrina and Fraser, Christophe
Antigen presentation from malaria infected liver cells – identifying better CD8+ T cell antigens (reference number 865) Spencer, Alexandra and Hill, Adrian
Arbovirus vaccine development: Zika, Dengue and Chikungunya (reference number 1069) Reyes-Sandoval, Arturo and Preciado-Llanes, Lorena
Biomarkers of the HIV reservoir - informing strategies towards HIV remission and cure (reference number 933) Frater, John Goulder, Professor Philip
Characterising Cancer Specific Cytotoxic T cells in patients with Metastasis Pleural Effusion (reference number 1056) Dong, Tao and Rahman, Najib Kannelakis, Nikolaos and Peng, Yanchun
Clinical, epidemiology and etiology of pediatric encephalitis in southern Vietnam (reference number 1037) Tan, Le Van and Hung, Nguyen Thanh and Irani, Sarosh
CMV and inflammatory bowel disease (reference number 951) Arancibia, Carolina Klenerman, Paul
CRISPR-activation and inhibition - manipulating gene expression within the stem cell (reference number 758) Davies, Ben and Knight, Julian
Cryo-EM, crystallography and functional studies of human membrane proteins involved in cancer, metabolic and neuropsychiatric disease (reference number 226) Carpenter, Liz and Pike, Dr Ashley
Defining the immune drivers of fibrotic pulmonary sarcoidosis (reference number 1054) Ho, Ling-Pei Denney, Dr Laura
Defining the role of co-infection and co-morbidity on tuberculosis vaccine immunity and efficacy (reference number 716) Tanner, Rachel and McShane, Helen and Satti, Iman and Stylianou, Dr Elena
Defining “response” to sepsis from electronic health records (reference number 1049) Walker, (Ann) Sarah Eyre, Dr David and Peto, Tim
Determining the optimal dose of mono-specific Daboia siamensis antivenom for systemic envenoming (reference number 1064) Smithuis, Frank and Ashley, Elizabeth
Development and characterisation of a new adjuvanted malaria vaccine (reference number 1050) Milicic, Anita and Hill, Adrian
Development of allosteric deubiquitinase targeted chimeras (DUBTACs) for protein activation and investigation of cellular ubiquitin signaling. (reference number 1071) Kessler, Benedikt and Brennan, Paul and Elliot, Paul
Development of combination therapies for MAGE-expressing tumours (reference number 1019) Eynde, Benoit Van Den and Leung, Dr Carol
Dissecting chemotaxis in the human parasite Leishmania (reference number 1052) Wheeler, Richard Sunter, Jack
DNA double-strand break repair equilibrium in tumour suppression and oncogenesis (reference number 658) Chapman, Ross and Ramadan, Kristijan
Drugging GTPases via Their Exchange Factors (reference number 1070) Brennan, Paul and von Delft, Frank
Elucidating the antigenic evolution of influenza to inform vaccine design (reference number 1028) Klenerman, Paul Gupta, Professor Sunetra
Emerging pathogens- vaccine development (reference number 750) Lambe, Teresa and Gilbert, Sarah and Hill, Adrian and Ewer, Katie
Epigenetic targets for immunomodulatory therapy in infectious disease and cancer (reference number 825) Knight, Julian and Davies, Ben
Exploring the role of CMV infection in TB susceptibility and TB vaccine immunogenicity and efficacy (reference number 1068) Satti, Iman and McShane, Helen
Health economic evaluation of direct-acting antivirals for hepatitis C treatment in Vietnam (reference number 1039) Thwaites, Guy and Turner, Hugo
Helper and regulatory cell interactions involved in control of humoral responses (reference number 1053) Borrow, Persephone and Bannard, Oliver Pedroza-Pacheco, Isabela
Identification of the protective characteristics of a promising TB vaccine candidate (reference number 745) McShane, Helen and Stylianou, Dr Elena
Identifying protective mechanisms of anti-sporozoite vaccines in humans. (reference number 1034) Ewer, Katie and Hill, Adrian
Improving viral genomic data analyses to gain new insights into HIV transmission and evolution (reference number 1011) Fraser, Christophe and McVean, Gil
Integrating structural and genomic information to understand cross-species transmission and evolution of emerging viruses (reference number 1072) Bowden, Thomas and Pybus, Professor Oliver
Investigating the therapeutic potential of a newly discovered cellular oxygen sensor (reference number 1058) Masson, Norma and Ratcliffe, Peter
Long-read and single-cell DNA epigenetic sequencing to study cancer heterogeneity (reference number 985) Song, Chunxiao and Lu, Xin and Kriaucionis, Skirmantas
Modelling integrated strategies for flavivirus diseases (reference number 1043) White, Lisa and Lourenco, Jose and Hancock, Penny
Molecular basis of moonlighting enzymes – the Swiss army knives in a cell (reference number 1048) Yue, Wyatt and Elkins, Jon
Molecular Mechanisms of genetic risk in atherosclerosis (reference number 1046) O'Callaghan, Chris and Davison, Professor Lucy
Predicting mortality and examining variation in outcomes for newborn units in Kenyan hospitals. (reference number 1047) English, Mike and Aluvaala, Jalemba
Re-engineering the DNA binding characteristics of a speciation gene (reference number 759) Myers, Simon and Davies, Ben and Donnelly, Peter
Roles of DNA modifications in epigenetic regulation of transcription (reference number 1066) Kriaucionis, Skirmantas and Goding, Colin
Socio-cultural context surrounding drivers of antibiotic consumption in Nam Dinh Province and the feasibility of community-targeted interventions (reference number 1036) Van Nuil, Jennifer and Lewycka, Sonia and Cheah, Phaik Yeong
Starvation and Pseudo-starvation in cancer metastasis (reference number 437) Goding, Colin and Kriaucionis, Skirmantas
Structural biology of cell surface receptors. (reference number 114) Jones, E. Yvonne and Stuart, David
Structural mechanisms of viral inhibition by host cell factors using cryoEM (reference number 866) Zhang, Peijun and Grimes, Jonathan
Structure and dynamics of bacterial chemotaxis signalling array by cryoEM (reference number 927) Zhang, Peijun and Sansom, Professor Mark
Structure, function and drug discovery for E3 ubiquitin ligases (reference number 1006) Bullock, Alex and D'Angiolella, Vincenzo
The application of epidemiological-economic models for policy guidance: the case of pertussis vaccination in South Africa (reference number 1059) Silal, Sheetal and White, Lisa
The role of RNA virus composition in pathogenicity and host response (reference number 814) Simmonds, Peter Fodor, Professor Ervin
Ubiquitin signalling in innate immune responses and cancer (reference number 1062) Gyrd-Hansen, Mads and Moura Alves, Pedro
Understanding pathways leading to severe dengue and predicting outcomes using biomarkers and physiological data from innovative wearable devices. (reference number 1035) Geskus, Ronald and Yacoub, Sophie and Phung Khanh, Lam
Understanding synergy of new cancer vaccines with PD1 checkpoint inhibitor blockade (reference number 1073) Redchenko, Irina and Eynde, Benoit Van Den
Understanding the impact of bacterial infections in causing pre-cancerous lesions (reference number 1033) Boccellato, Francesco and Goding, Colin
Using mathematical modelling to inform diagnostic strategies for febrile illnesses in the context of universal health care (reference number 998) Dittrich, Dr Sabine and White, Lisa and Pan-ngum, Wirichada
What is the effect of genetic variation on B and T cell fate and disease susceptibility? (reference number 981) Bashford-Rogers, Rachael and Todd, John
Zoonotic viruses at the cell surface (reference number 1065) Bowden, Thomas and Zhang, Peijun