Immune response may be harnessed to control HIV
11 March 2025
Researchers have unveiled primary trial results that show encouraging advances in HIV treatment driven by immune-based therapies. New antibody therapies could offer alternative to current treatments.
Oxford and GSK launch £50m programme to advance cancer research
27 January 2025
Global biopharma company GSK invests up to £50 million in a collaboration with Oxford to advance the understanding of how cancer develops, which could inform future development of vaccines to prevent cancer.
Fitness compensation in m.tuberculosis: a game of genetic chess
27 February 2024
Viktoria Brunner takes us behind the scenes of their latest publication 'Compensatory mutations are associated with increased in vitro growth in resistant clinical samples of Mycobacterium tuberculosis' published in Microbial Genomics.
Emerging Leaders Prize recognises future leaders in hepatitis research
7 December 2023
Three outstanding hepatitis researchers have been announced today as winners of the Medical Research Foundation’s seventh Emerging Leaders Prize.
A global collaboration to develop next-generation COVID-19 and flu vaccines
10 October 2023
Today Oxford University has launched a new global collaboration backed by £8 million funding from UK Research and Innovation (UKRI). The project will be spearheaded by Professor Teresa Lambe, Professor of Vaccinology and Immunology and Calleva Head of Vaccine Immunology in the Department of Paediatrics and Professor Paul Klenerman, Sidney Truelove Professor of Gastroenterology and Director of the Translational Gastroenterology Unit at NDM, both of whom are Principal Investigators at NDM’s Pandemic Sciences Institute.
Study reveals vaccine response in patients with impaired immune systems
6 July 2023
Updated data from the ongoing OCTAVE trial, a collaboration between the Universities of Glasgow, Birmingham and Oxford, show for the first time that most clinically at-risk patients with a range of immunocompromised or immunosuppressed conditions in the UK were protected from severe COVID by the vaccination programme.
3.4 million assays run by NDM’s serology platform
7 June 2023
Within weeks of the pandemic starting, the Nuffield Department of Medicine (NDM) began antibody testing as part of the UK’s ONS COVID-19 Infection Survey. The platform successfully tested millions of blood samples over three years, providing invaluable information on how vaccinations and previous infections affect the chance of getting COVID-19 again.
Landmark antibody study to test immune responses against COVID-19
17 April 2023
Thousands of immunosuppressed people, including patients at Oxford University Hospitals (OUH), have the chance to take part in a landmark new study investigating which people are still at the greatest risk of COVID-19 infection after vaccination.
COVID-19: accelerating testing with robotics
3 April 2023
Kevin Chau, a PhD student on our National PhD Training Programme in AMR Research, has contributed to the pandemic response as part of the Modernising Medical Microbiology team at John Radcliffe Hospital in Oxford. In a new blog post, he describes the experience.
Three NDM researchers awarded Associate Professorships
5 January 2023
We are delighted to announce that three researchers have been awarded the Associate Professor title, in recognition of their research achievements, contribution to teaching, and contribution to the general work of the Nuffield Department of Medicine.
Paediatric IBD BioResource opens to support vital research
3 May 2022
A new National Institute for Health and Care Research (NIHR) BioResource aimed at investigating inflammatory bowel disease (IBD) in children has opened, with the NIHR Oxford BRC playing a key role.
Low Back Pain Trial
4 April 2022
The Oxford Bone Infection Research Group NDMOxford is recruiting patients into a new clinical trial for patients with chronic low back pain. To find out more visit http://lowbackpainstudy.co.uk
Oxford academics named NIHR Senior Investigators
8 March 2022
Seven academics in Oxford have been named National Institute of Health Research (NIHR) Senior Investigators in recognition of their outstanding leadership in research.
Monitoring Populations at risk from Coronavirus
25 November 2021
Emma Pritchard, Statistician and PhD student shares her work with ONS on Coronavirus statistics.
Oxford and Oracle partner to speed identification of COVID-19 variants
21 September 2021
The fast spread of the highly infectious Delta variant underscores the need for faster identification of COVID-19 mutations. Uniting governments and medical communities in this challenge, the University of Oxford and Oracle’s Global Pathogen Analysis System (GPAS) is now being used by organizations on nearly every continent. Institutions using the platform include: the University of Montreal Hospital Centre Research Centre, the Institute of Public Health Research of Chile, the Oxford University Clinical Research Unit in Vietnam, the Institute of Clinical Pathology and Medical Research – New South Wales Pathology, and Oxford Nanopore Technologies. GPAS is also now part of the Public Health England New Variant Assessment Platform.
Finding our Way - An NHS Tribute Garden
20 September 2021
‘Finding Our Way – An NHS Tribute Garden’ is a celebration of the incredible efforts of the thousands of people who fought – and are still fighting - the COVID-19 pandemic on our behalf. Designed by Naomi Ferrett-Cohen and presented by Oxford University Hospitals NHS Foundation Trust and Oxford University.
T-cell ‘training grounds’ behind robust immune system response seen in adenovirus vaccines
31 August 2021
Writing in the journal Nature Immunology, they detail an investigation into one of the key features of adenovirus vaccines – their ability to generate strong and sustained populations of the ‘killer’ T-cell element of the immune system.