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Evaluation of LamPORE rapid tests for Covid-19 show high levels of diagnostic sensitivity

Scientists from the University of Oxford’s Nuffield Department of Medicine have today published their evaluation of LamPORE, a novel diagnostic platform for detecting SARS-CoV-2 RNA. It combines loop-mediated isothermal amplification with nanopore sequencing. This technology has the potential to analyse thousands of samples per day on a single instrument.

Two new Wellcome Investigator Awards at the MRC WIMM

Many congratulations to Prof Anne Goriely and Prof Alison Simmons, who have both been awarded Wellcome Trust Investigator Awards.

New NDM Professors

The Medical Sciences Divisional Panel has conferred the title of Professor on six members of NDM's academic staff.

TGU, University of Oxford Awarded the IBD Stress Test QuickFire Challenge

Johnson & Johnson Innovation - JLABS announced on 11th July that the Translational Gastroenterology Unit, University of Oxford, has been selected as the awardee in the IBD Stress Test QuickFire Challenge.

Eight Oxford researchers elected Fellows of the Academy of Medical Sciences

Eight Oxford scientists are amongst 50 of the UK's world-leading researchers elected to join the prestigious Fellowship of the Academy of Medical Sciences this year.

The silent epidemic killing more people than HIV, malaria or TB

Viral hepatitis is on the rise. Tackling hepatitis B in Africa is key to fighting back. “HIV has been an acute pandemic with resources thrown at it.

Professor Peter Ratcliffe recieves Knighthood in New Years Honours

For services to Clinical Medicine, Peter Radcliffe, Head of the Nuffield Department of Clinical Medicine, and Fellow of Magdalen College recieved a Knighthood in the New Year Honours.

Mortality risks associated with emergency admissions during weekends and public holidays

An analysis of antibiotic use at the John Radcliffe hospital has shown that some Doctors use up to 30% less antibiotics without risk to patients. However they may admit more patients when the diagnosis is unclear - a ‘hold and observe’ strategy as opposed to ‘prescribe antibiotics and discharge’.

Online tool allows patients with ulcerative colitis to manage condition

Following a successful clinical trial, Dr Alissa Walsh, the main researcher, who works with Professor Simon Travis, has spoken about the online tool that allows people with a form of inflammatory bowel disease (IBD) to manage their own condition and reduce hospital visits. This is now being rolled out to more patients in Oxford who suffer from ulcerative colitis.

World Asthma Day Research Update

Asthma is a chronic disease of the airways that is on the increase. 5.4 million people receive asthma medications in the UK each year. That is 1:12 adults and 1:11 children. Asthma is treatable and it is frustrating that despite the amount of treatment prescribed, one patient with asthma has an attack every ten seconds, and approximately 17% of asthma patients find it a disease difficult to.

New potential treatment target for inflammatory bowel disease patients

Oxford Researchers have identified a potential therapeutic target for inflammatory bowel diseases. The findings are of particular importance to the 40% of patients who don’t respond to anti-TNF therapy, the current treatment option available. Professor Simon Travis co-led this study.

Consensus statement: Virus taxonomy in the age of metagenomics

Although viral sequences are important in traditional taxonomy, information used for virus classification typically requires information on their biological properties, such as host range, pathogenicity and virion structure as well as genetic relationships. In his recent Consensus statement, Professor Peter Simmonds proposes sequence-only classification, enabling much of the viral diversity observed in metagenomic sequence datasets to be incorporated into official virus taxonomy.

Graduate Study Prize Winners 2016

The NDM Graduate Prize winners for 2016 are Emma Davenport, Symon Kariuki, Sarah McCuaig, Manuel Rivas and Joshua Tan. The winners were awarded a £500 prize. This year’s winners have worked across many research areas including malaria vaccine work, behavioural studies and software development.

Professor Sir Peter Ratcliffe wins Lasker research awards

Professor Sir Peter Ratcliffe has won one of the most prestigious prizes in medicine. The Lasker Awards recognise contributions that have allowed major advances in the understanding, diagnosis, treatment, and prevention of human disease. Professor Ratcliffe is to receive the prizes for his work understanding the mechanisms by which cells sense and signal hypoxia (low oxygen levels), an important component of many human diseases including cancer, heart disease, stroke, vascular disease, and anaemia.

Medicine at Oxford named world's best for sixth year running

Medical and health teaching and research at Oxford University has been ranked as the world's best for the sixth year running in the Times Higher Education World University Rankings. The discipline-specific tables, released today, follow on from last week's announcement that Oxford has been ranked the top university in the world by the same publication - the first time a UK institution has been awarded the accolade.

Oxford ranked first among global universities

Oxford becomes the first British university ever to occupy top position in the global table, which judges the performance of 980 universities across 79 countries. Oxford’s top ranking reflects its all-round strength in contemporary research and teaching. Renowned as the oldest University in the English speaking world, modern Oxford is at the forefront of the full range of academic disciplines, including medical sciences, science and engineering, humanities and social sciences.

Researchers find more uses for immune system's 'Swiss army knife'

Mucosal Associated Invariant T-cells (MAIT cells) Australian researchers recently found that they had an important role in fighting bacterial infections. Now, the Oxford team, led by Professor Paul Klenerman, say that they also fight viruses. Their results are in the journal Nature Communications.

Volunteers needed for gut flora study

Dr Nicola Fawcett from the Modernising Medical Microbiology research group writes in the Oxford Mail about her research on the human microbiome, and how it might be affected by medications such as antibiotics.

How effective are pain medications for lung conditions?

Dr Najib Rahman has led a study that challenges current guidelines that advocate the avoidance of nonsteroidal anti-inflammatory drugs (NSAIDs) and use of small chest tubes for a specific lung condition.

Revealing 'hidden' HIV

Talking to BBC Radio Oxford, Professor John Frater describes how HIV hides from the immune system, and how a new trial hopes to get the virus to reveal itself, so that the immune system can kill it. Interview begins approximately five minutes from the start of the programme.

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