About the TGU
The Translational Gastroenterology Unit hosts teams of scientists and clinicians working together to tackle major diseases affecting the gut and the liver. This includes cancers, infections and inflammatory diseases. A longstanding interest of the unit is inflammatory bowel disease (ulcerative colitis and Crohn’s disease), dating back to the era of Sidney Truelove, who developed the first trials and treatments. Together we are now pursuing studies of vaccines, diagnostics, biomarkers, genetics and new clinical interventions in a range of diseases including celiac disease, intestinal failure and auto-immune liver diseases. The unit hosts the Sidney Truelove chair and the Lee Placito chair and around 15 PIs across the different university sites who study various aspects of GI disease at the interface of clinical medicine and basic science. It also hosts a core Flow Cytometry Facility that offers a high-quality Flow Cytometry service to a variety of users. The TGU and flow cytometry facility are supported by the Biomedical Research Centre and Human Immune Discovery Initiative.
Incidence of HIV and hepatitis C virus among people who inject drugs, and associations with age and sex or gender: a global systematic review and meta-analysis
Artenie A. et al, (2023), The Lancet Gastroenterology & Hepatology, 8, 533 - 552
Subcellular protein localisation of Trypanosoma brucei bloodstream form-upregulated proteins maps stage-specific adaptations
Halliday C. et al, (2023), Wellcome Open Research, 8, 46 - 46
News and Events
Crohn’s & Colitis Public Information Event - 21st March 2023
17 January 2023
21st March 2023 5:30-7:30 PM, Lecture Theatre 1, John Radcliffe Hospital, Oxford OX3 9DU. Patients, the public and healthcare professionals welcome. Registration for this event is now closed.
Workshop: Clinical Genomics in Inflammatory Bowel Disease - 25th April 2023
16 January 2023
A proportion of patients with Inflammatory bowel disease (IBD) may have a known genetic cause. For those exceptionally rare conditions, the NHS has commissioned genomic testing in specific patient groups. The successful implementation and progression of clinical genomics for IBD requires multi-disciplinary care, specialist knowledge and establishment of networks. Within this workshop, hosted by the monogenic IBD team from the Central and South Genomic Medicine Service Alliance, we aim to discuss clinical care for these patients, practical implementation of clinical genomics and discuss specific monogenic cases. This workshop is targeted at paediatric gastroenterologists, trainees, nurse specialists, immunologists, clinical geneticists, paediatricians with an interest in GI disorders and adult gastroenterologists.
Featured TGU Researcher
I am a molecular and cellular biologist by training, but I have always applied this basic research skills to study human health and diseases.
TGU Talk: "Inflammation and dysmetabolism: denominators in childhood wasting and poor clinical outcomes" by Dr James Njunge
Thursday, 01 June 2023, 4.30pm to 6pm