About the TGU
The Translational Gastroenterology Unit hosts teams of scientists and clinicians working together to tackle major diseases affecting the gut and the liver. This includes cancers, infections and inflammatory diseases. A longstanding interest of the unit is inflammatory bowel disease (ulcerative colitis and Crohn’s disease), dating back to the era of Sidney Truelove, who developed the first trials and treatments. Together we are now pursuing studies of vaccines, diagnostics, biomarkers, genetics and new clinical interventions in a range of diseases including celiac disease, intestinal failure and auto-immune liver diseases. The unit hosts the Sidney Truelove chair and the Lee Placito chair and around 15 PIs across the different university sites who study various aspects of GI disease at the interface of clinical medicine and basic science. It also hosts a core Flow Cytometry Facility that offers a high-quality Flow Cytometry service to a variety of users. The TGU and flow cytometry facility are supported by the Biomedical Research Centre and Human Immune Discovery Initiative.
Latest publications
-
A systematic review of Hepatitis B virus (HBV) prevalence and genotypes in Kenya: Data to inform clinical care and health policy
Journal article
Downs LO. et al, (2023), PLOS Global Public Health, 3, e0001165 - e0001165
-
Subcellular protein localisation of Trypanosoma brucei bloodstream form-upregulated proteins maps stage-specific adaptations
Journal article
Halliday C. et al, (2023), Wellcome Open Research, 8, 46 - 46
News and Events
Crohn’s & Colitis Public Information Event
17 January 2023
21st March 2023 5:30-7:30 PM, Lecture Theatre 1, John Radcliffe Hospital, Oxford OX3 9DU. Patients, the public and healthcare professionals welcome
Workshop: Clinical Genomics in Inflammatory Bowel Disease - 25th April 2023
16 January 2023
A proportion of patients with Inflammatory bowel disease (IBD) may have a known genetic cause. For those exceptionally rare conditions, the NHS has commissioned genomic testing in specific patient groups. The successful implementation and progression of clinical genomics for IBD requires multi-disciplinary care, specialist knowledge and establishment of networks. Within this workshop, hosted by the monogenic IBD team from the Central and South Genomic Medicine Service Alliance, we aim to discuss clinical care for these patients, practical implementation of clinical genomics and discuss specific monogenic cases. This workshop is targeted at paediatric gastroenterologists, trainees, nurse specialists, immunologists, clinical geneticists, paediatricians with an interest in GI disorders and adult gastroenterologists.
Featured TGU Researcher
Eoghan Mulholland
"Perhaps a cliché, but I like that no two days are the same"
Oxtalks Feed
-
Tuesday, 21 March 2023, 5.30pm to 7.30pm
-
Tuesday, 25 April 2023, 10am to 4pm