Oxford Respiratory Trials Unit (ORTU)
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About ORTU
The Oxford Respiratory Trials Unit (ORTU) is a Clinical Trials Unit which specialises in the design, delivery, analysis and administration of trials across the broad scope of Respiratory Medicine and Respiratory Diseases.
We run national and international trials related to our academic areas of interest, as well as supporting trials led by other teams and industry. Our scope of work includes clinical trials at all phases, including translational studies, phase II discovery studies and multicentre definitive randomised trials.
We partner with a broad range of academic funders (National Institute of Health Research, Medical Research Council, British Lung Foundation, National Cancer Research Institute, CRUK) and partners in industry. Key funding for ORTU is derived from the NIHR Research Delivery Network (RDN) and the Oxford NIHR Biomedical Research Centre.
ORTU publications
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Prognostic significance of pleural fluid microbiological positivity in pleural infection: a bicentric 10-year retrospective observational study.
Wong C. et al, (2025), Respiratory research, 26
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Multidisciplinary management of adult patients with chylothorax: a consensus statement.
Agrawal A. et al, (2024), The European respiratory journal, 64
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Chest Tubes and Pleural Drainage: History and Current Status in Pleural Disease Management
Sorino C. et al, (2024), Journal of Clinical Medicine, 13, 6331 - 6331
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Pro: indwelling pleural catheters cause harm to patients.
Iqbal B. et al, (2024), Breathe (Sheffield, England), 20
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Complicated Pleural Infection is Associated With Prolonged Recovery and Reduced Functional Ability.
Meggyesy AM. et al, (2024), Journal of bronchology & interventional pulmonology, 31
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Reply: Guideline recommendations don't exist in a vacuum.
Walker S. et al, (2024), The European respiratory journal, 64
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Navigational Bronchoscopy vs CT Scan-Guided Transthoracic Needle Biopsy for the Diagnosis of Indeterminate Lung Nodules: Protocol and Rationale for the Navigation Endoscopy to Reach Indeterminate Lung Nodules vs Transthoracic Needle Aspiration, a Randomized Controlled Study Multicenter Randomized Trial
Lentz RJ. et al, (2024), CHEST Pulmonary, 2
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1-year health outcomes associated with systemic corticosteroids for COVID-19: a longitudinal cohort study.
Leavy OC. et al, (2024), ERJ open research, 10, 474 - 2024