Oxford Respiratory Trials Unit (ORTU)
About ORTU
The Oxford Respiratory Trials Unit (ORTU) is a Clinical Trials Unit which specialises in the design, delivery, analysis and administration of trials across the broad scope of Respiratory Medicine and Respiratory Diseases.
We run national and international trials related to our academic areas of interest, as well as supporting trials led by other teams and industry. Our scope of work includes clinical trials at all phases, including translational studies, phase II discovery studies and multicentre definitive randomised trials.
We partner with a broad range of academic funders (National Institute of Health Research, Medical Research Council, British Lung Foundation, National Cancer Research Institute, CRUK) and partners in industry. Key funding for ORTU is derived from the NIHR Research Delivery Network (RDN) and the Oxford NIHR Biomedical Research Centre.
ORTU publications
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Incidence of discordant pleural fluid exudates and diagnostic patterns - a retrospective cohort study.
Journal article
Addala DN. et al, (2025), Chest
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Validating data from multiplex assays of variant effect: A CanVIG-UK national survey of NHS clinical scientists.
Journal article
Allen S. et al, (2025), American journal of human genetics, 112, 1479 - 1488
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Breast cancer germline multigene panel testing in mainstream oncology based on clinical-public health utility: ESMO Precision Oncology Working Group recommendations.
Journal article
Turnbull C. et al, (2025), Annals of oncology : official journal of the European Society for Medical Oncology
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Medullary Thyroid Cancer Risk and Mortality in Carriers of Incidentally Identified MEN2A RET Variants.
Journal article
West CE. et al, (2025), JAMA network open, 8
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Navigational Bronchoscopy or Transthoracic Needle Biopsy for Lung Nodules.
Journal article
Lentz RJ. et al, (2025), The New England journal of medicine, 392, 2100 - 2112
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Impact of GLP-1 receptor agonist-induced weight loss on 22 cancers in the next ten years using a Markov state-transition model - A UK weight and wellness cancer landscape analysis.
Journal article
Dong J. et al, (2025), Cancer Epidemiol, 97
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Pneumothorax: An update on clinical spectrum, diagnosis and management
Journal article
Iqbal B. et al, (2025), Clinical Medicine, 25, 100327 - 100327
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Retrospective analysis of the sensitivity of reporting of thoracic computed tomography for pleural malignancy: an Australian multi-centre study
Journal article
Graffen SC. et al, (2025), Journal of Thoracic Disease, 17, 1958 - 1966