About
The Experimental Medicine Division is a collection of research groups within the Nuffield Department of Medicine who are based at a number of sites including the John Radcliffe Hospital, the Peter Medawar Building for Pathogen Research, the Churchill Hospital, the Old Road Campus, the Nuffield Orthopaedic Hospital and the Weatherall Institute of Molecular Medicine.
Our researchers seek to understand the pathophysiology of disease and apply this knowledge to develop enhanced diagnostics and treatments for human disease. Our research spans fundamental basic science to translational and experimental medicine approaches including clinical trials. Areas of focus includes immunology, behavioural science, infectious diseases, gastroenterology, palliative care and respiratory medicine.
News
Immune response may be harnessed to control HIV
11 March 2025
Oxford and GSK launch £50m programme to advance cancer research
27 January 2025
TWiM 303: Can our microbiome break our hearts?
4 March 2024
Publications
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MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines
Journal article
Amini A. et al, (2025), Science Immunology, 10
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Dosing interval is a major factor determining the quality of T cells induced by SARS-CoV-2 mRNA and adenoviral vector vaccines
Journal article
Murray SM. et al, (2025), Science Immunology, 10
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TCF1 and LEF1 promote B-1a cell homeostasis and regulatory function.
Journal article
Shen Q. et al, (2025), Nature