Publications
Latest publications
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Antimicrobial usage among acutely ill hospitalised children aged 2‒23 months in sub-Saharan Africa and South Asia
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Tigoi C. et al, (2025), Open Forum Infectious Diseases
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Comparative performance of the InBios SCoV-2 DetectTM IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations
Journal article
Kutima B. et al, (2025), Wellcome Open Research, 9, 349 - 349
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Timeliness of a potential automated system for national surveillance of healthcare-associated infections in England
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Quan TP. et al, (2025), Journal of Hospital Infection, 161, 10 - 12
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Community-acquired pneumonia identification from electronic health records in the absence of a gold standard: A Bayesian latent class analysis.
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Wei J. et al, (2025), PLOS digital health, 4
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Pf8: an open dataset of Plasmodium falciparum genome variation in 33,325 worldwide samples
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Abdel Hamid MM. et al, (2025), Wellcome Open Research, 10, 325 - 325
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An improved catalogue for whole-genome sequencing prediction of bedaquiline resistance in Mycobacterium tuberculosis using a reproducible algorithmic approach
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Adlard D. et al, (2025), Microbial Genomics, 11
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Epidemiology and excess mortality of antimicrobial resistance in bacteraemias among cancer patients: a cohort study using routinely collected health data from regional hospital trusts in Oxford and Oslo, 2008-2018.
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Danielsen AS. et al, (2025), BMJ Open, 15
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Establishing laboratory reference ranges for haematological and biochemical blood parameters in adults and children in Kilifi, Kenya
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Downs LO. et al, (2025), Wellcome Open Research, 10, 312 - 312
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To heal or harm: a systematic review of the role of fluoroquinolones in periprosthetic joint infections
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Tevell S. et al, (2025), CMI Communications, 105103 - 105103
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COVID-19 mortality in Africa and Asia - Authors' reply.
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Bejon P. et al, (2025), Lancet Infect Dis
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A pragmatic randomized controlled trial of standard care versus corticosteroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals (SONIA)
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Lucinde R. et al, (2025), Wellcome Open Research, 7, 269 - 269
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Identification of undetected SARS-CoV-2 infections by clustering of Nucleocapsid antibody trajectories
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Zwerwer LR. et al, (2025), Nature Communications, 16
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Key SARS-CoV-2 testing strategies implemented in the UK: rationale and impact.
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Fowler T. et al, (2025), Journal of the Royal Society of Medicine, 118, 112 - 120
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Transformers and large language models are efficient feature extractors for electronic health record studies
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Yuan K. et al, (2025), Communications Medicine, 5
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Molecular clock complexities of Clostridioides difficile.
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Vernon JJ. et al, (2025), Anaerobe
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Publisher Correction: Muscle abnormalities in Long COVID.
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Ranque B. et al, (2025), Nature communications, 16
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Low-Dose Yellow Fever Vaccine in Adults in Africa
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Kimathi D. et al, (2025), New England Journal of Medicine, 392, 788 - 797
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The impact of antimicrobial stewardship ward rounds on antimicrobial use and predictors of advice, uptake, and outcomes
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Eyre DW. et al, (2025), Journal of Infection, 90, 106419 - 106419
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Reply: Muscle abnormalities in Long COVID.
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Ranque B. et al, (2025), Nature communications, 16
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Machine learning and clinician predictions of antibiotic resistance in Enterobacterales bloodstream infections
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Yuan K. et al, (2025), Journal of Infection, 90, 106388 - 106388
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P-260. Antibiotic residues in hospital sink p-trap water in Kilifi, Kenya
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Hookham L. et al, (2025), Open Forum Infectious Diseases, 12
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Predicting rifampicin resistance inM. tuberculosisusing machine learning informed by protein structural and chemical features
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Lynch CI. et al, (2025), ERJ Open Research, 00952 - 2024
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Multiple introductions of NRCS-A Staphylococcus capitis to the neonatal intensive care unit drive neonatal bloodstream infections: a case-control and environmental genomic survey
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Lees EA. et al, (2025), Microbial Genomics, 11
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Comparative evaluation of swabbing sites for Omicron variant detection in PCR testing.
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Fowler T. et al, (2025), Diagnostic microbiology and infectious disease, 111
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Effectiveness and user experience of nose and throat swabbing techniques for SARS-CoV-2 detection: results from the UK COVID-19 National Testing Programme.
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Futschik ME. et al, (2025), BMC global and public health, 3
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Developing a framework for tracking antimicrobial resistance gene movement in a persistent environmental reservoir
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Mathers AJ. et al, (2024), npj Antimicrobials and Resistance, 2
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Addition of Macrolide Antibiotics for Hospital Treatment of Community-Acquired Pneumonia
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Wei J. et al, (2024), The Journal of Infectious Diseases
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Kinetics of naturally induced binding and neutralising anti-SARS-CoV-2 antibody levels and potencies among SARS-CoV-2 infected Kenyans with diverse grades of COVID-19 severity: an observational study
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Kimotho J. et al, (2024), Wellcome Open Research, 8, 350 - 350
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Detecting changes in population trends in infection surveillance using community SARS-CoV-2 prevalence as an exemplar
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Pritchard E. et al, (2024), American Journal of Epidemiology, 193, 1848 - 1860
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Global genomic epidemiology of <i>bla</i> <sub>GES-5</sub> carbapenemase-associated integrons.
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Matlock W. et al, (2024), Microbial genomics, 10
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Corrigendum to “No evidence of difference in mortality with amoxicillin versus co-amoxiclav for hospital treatment of community-acquired pneumonia” [J Infect 88 (2024) 106161]
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Wei J. et al, (2024), Journal of Infection, 89, 106361 - 106361
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Predicting individual patient and hospital-level discharge using machine learning
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Wei J. et al, (2024), Communications Medicine, 4
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Footprints of innate immune activity during HIV-1 reservoir cell evolution in early-treated infection
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Sun W. et al, (2024), Journal of Experimental Medicine, 221
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A Comparison of Causative Pathogens in Bone and Prosthetic Joint Infections: Implications for Antimicrobial Therapy.
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Unsworth A. et al, (2024), Antibiotics (Basel, Switzerland), 13
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The use of antibiotic-loaded calcium sulphate beads in debridement, antibiotics, and implant retention (DAIR) for periprosthetic infections: a retrospective comparative cohort on outcome.
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Sigmund IK. et al, (2024), Acta orthopaedica, 95, 707 - 714
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Identification of complex Plasmodium falciparum genetic backgrounds circulating in Africa: a multicountry genomic epidemiology analysis.
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Miotto O. et al, (2024), The Lancet. Microbe
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Prospective clinical surveillance for severe acute respiratory illness and COVID-19 vaccine effectiveness in Kenyan hospitals during the COVID-19 pandemic.
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Lucinde RK. et al, (2024), BMC infectious diseases, 24
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Exploring uncatalogued genetic variation in antimicrobial resistance gene families in Escherichia coli: an observational analysis
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Lipworth S. et al, (2024), The Lancet Microbe, 5, 100913 - 100913
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Comparison of direct cDNA and PCR-cDNA Nanopore sequencing of RNA from Escherichia coli isolates
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Rodger G. et al, (2024), Microbial Genomics, 10
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Diversity, functional classification and genotyping of SHV β-lactamases in Klebsiella pneumoniae
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Tsang KK. et al, (2024), Microbial Genomics, 10
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Effects of the COVID-19 pandemic on hospital admissions and inpatient mortality in Kenya: a retrospective cohort study
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Ogero MO. et al, (2024), Wellcome Open Research, 9, 582 - 582
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How, why and when are delayed (back-up) antibiotic prescriptions used in primary care? A realist review integrating concepts of uncertainty in healthcare
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Mcleod M. et al, (2024), BMC Public Health, 24
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Predicting future hospital antimicrobial resistance prevalence using machine learning
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Vihta K-D. et al, (2024), Communications Medicine, 4
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Dissemination and persistence of antimicrobial resistance (AMR) along the wastewater-river continuum
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Read DS. et al, (2024), Water Research, 264, 122204 - 122204
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Antibodies to PfEMP1 and variant surface antigens: Protection after controlled human malaria infection in semi-immune Kenyan adults.
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Kinyua AW. et al, (2024), The Journal of infection, 89
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Genomic epidemiology and longitudinal sampling of ward wastewater environments and patients reveals complexity of the transmission dynamics of blaKPC-carbapenemase-producing Enterobacterales in a hospital setting
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Stoesser N. et al, (2024), JAC-Antimicrobial Resistance, 6
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Global, regional, and national incidence and mortality burden of non-COVID-19 lower respiratory infections and aetiologies, 1990-2021: a systematic analysis from the Global Burden of Disease Study 2021.
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GBD 2021 Lower Respiratory Infections and Antimicrobial Resistance Collaborators None., (2024), The Lancet. Infectious diseases, 24, 974 - 1002
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A retrospective analysis of P. falciparum drug resistance markers detects an early (2016/17) high prevalence of the k13 C469Y mutation in asymptomatic infections in Northern Uganda.
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Ogwang R. et al, (2024), Antimicrobial agents and chemotherapy, 68
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Expanding the use of mathematical modeling in healthcare epidemiology and infection prevention and control.
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Grant R. et al, (2024), Infection control and hospital epidemiology, 1 - 6
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Double testing with lateral flow antigen test devices for COVID-19: does a second test in quick succession add value?
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Futschik ME. et al, (2024), Journal of virological methods, 329
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Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050
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Naghavi M. et al, (2024), The Lancet, 404, 1199 - 1226
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Infection Inspection: using the power of citizen science for image-based prediction of antibiotic resistance in Escherichia coli treated with ciprofloxacin
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Farrar A. et al, (2024), Scientific Reports, 14
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The mRNA content of plasma extracellular vesicles provides a window into molecular processes in the brain during cerebral malaria
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Kioko M. et al, (2024), Science Advances, 10
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Quantitative drug susceptibility testing for Mycobacterium tuberculosis using unassembled sequencing data and machine learning
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(2024), PLOS Computational Biology, 20, e1012260 - e1012260
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Full-length MSP1 is a major target of protective immunity after controlled human malaria infection.
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Rosenkranz M. et al, (2024), Life science alliance, 7
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MmpR5 protein truncation and bedaquiline resistance in Mycobacterium tuberculosis isolates from South Africa: a genomic analysis.
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Roberts LW. et al, (2024), The Lancet. Microbe, 5
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Self-swabbing versus assisted swabbing for viral detection by qRT-PCR: the experience from SARS-CoV-2 based on a meta-analysis of six prospectively designed evaluations conducted in a UK setting.
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Fowler T. et al, (2024), European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 43, 1621 - 1630
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Retrospective analysis of hospital electronic health records reveals unseen cases of acute hepatitis with unknown aetiology in adults in Oxfordshire
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Tan CCS. et al, (2024), BMC Public Health, 24
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The implementation of whole-genome sequencing for <i>Mycobacterium tuberculosis</i> in Vietnam.
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Huong DT. et al, (2024), IJTLD open, 1, 320 - 322
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Linking Cerebral Malaria Pathogenesis to APOE-Mediated Amyloidosis: Observations and Hypothesis.
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Kioko M. et al, (2024), Molecular neurobiology
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Comparative performance of the InBios SCoV-2 DetectTM IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations
Journal article
Kutima B. et al, (2024), Wellcome Open Research, 9, 349 - 349
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Improving the representativeness of UK’s national COVID-19 Infection Survey through spatio-temporal regression and post-stratification
Journal article
Pouwels KB. et al, (2024), Nature Communications, 15
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Utility of MALDI-TOF MS for determination of species identity and blood meal sources of primary malaria vectors on the Kenyan coast
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Karisa J. et al, (2024), Wellcome Open Research, 8, 151 - 151
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Nanopore sequencing of influenza A and B in Oxfordshire and the United Kingdom, 2022–23
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Cane J. et al, (2024), Journal of Infection, 88, 106164 - 106164
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Breadth of Fc-mediated effector function correlates with clinical immunity following human malaria challenge.
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Nkumama IN. et al, (2024), Immunity, 57, 1215 - 1224.e6
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No evidence of difference in mortality with amoxicillin versus co-amoxiclav for hospital treatment of community-acquired pneumonia
Journal article
Wei J. et al, (2024), Journal of Infection, 88, 106161 - 106161
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A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial)
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Maitland K. et al, (2024), Wellcome Open Research, 9, 281 - 281
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Assessment of three antibiotic combination regimens against Gram-negative bacteria causing neonatal sepsis in low- and middle-income countries
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Kakaraskoska Boceska B. et al, (2024), Nature Communications, 15
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Evaluation of the accuracy of bacterial genome reconstruction with Oxford Nanopore R10.4.1 long-read-only sequencing
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Sanderson ND. et al, (2024), Microbial Genomics, 10
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Tungiasis among children in Kenya is associated with poor nutrition status, absenteeism, poor school performance and high impact on quality of life.
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Elson L. et al, (2024), PLoS neglected tropical diseases, 18
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Distinct patterns of vital sign and inflammatory marker responses in adults with suspected bloodstream infection
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Gu Q. et al, (2024), Journal of Infection, 88, 106156 - 106156
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Rifampicin resistant Mycobacterium tuberculosis in Vietnam, 2020-2022.
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Van Nguyen H. et al, (2024), Journal of clinical tuberculosis and other mycobacterial diseases, 35
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Author Correction: The plasmidome associated with Gram-negative bloodstream infections: a large-scale observational study using complete plasmid assemblies
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Lipworth S. et al, (2024), Nature Communications, 15
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Distinct patterns of vital sign and inflammatory marker responses in adults with suspected bloodstream infection.
Journal article
Gu Q. et al, (2024), The Journal of infection
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Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi
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Asante KP. et al, (2024), The Lancet, 403, 1660 - 1670
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Rapid antigen testing for SARS-CoV-2 by lateral flow assay: A field evaluation of self- and professional testing at UK community testing sites.
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Futschik ME. et al, (2024), Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 171
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SARS-CoV-2, influenza A/B and respiratory syncytial virus positivity and association with influenza-like illness and self-reported symptoms, over the 2022/23 winter season in the UK: a longitudinal surveillance cohort
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Dietz E. et al, (2024), BMC Medicine, 22
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Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine-learning approaches
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Carter JJ. et al, (2024), JAC-Antimicrobial Resistance, 6
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The plasmidome associated with Gram-negative bloodstream infections: A large-scale observational study using complete plasmid assemblies
Journal article
Lipworth S. et al, (2024), Nature Communications, 15
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Compensatory mutations are associated with increased in vitro growth in resistant clinical samples of Mycobacterium tuberculosis
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Brunner VM. and Fowler PW., (2024), Microbial Genomics, 10
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Risk of SARS-CoV-2 reinfection during multiple Omicron variant waves in the UK general population
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Wei J. et al, (2024), Nature Communications, 15
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Fourth Controlled Human Infection Model (CHIM) meeting – CHIMs in endemic countries, May 22–23, 2023
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Kapulu M. et al, (2024), Biologicals, 85, 101747 - 101747
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Safety and efficacy of malaria vaccine candidate R21/Matrix-M in African children: a multicentre, double-blind, randomised, phase 3 trial
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Datoo MS. et al, (2024), The Lancet, 403, 533 - 544
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A workflow for the detection of antibiotic residues, measurement of water chemistry and preservation of hospital sink drain samples for metagenomic sequencing
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Rodger G. et al, (2024), Journal of Hospital Infection, 144, 128 - 136
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Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach
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Barilar I. et al, (2024), Nature Communications, 15
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Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected.
Journal article
Kimenyi KM. et al, (2024), BMC infectious diseases, 24
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Comparative performance of the InBios SCoV-2 Detect TM IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations.
Journal article
Kutima B. et al, (2024), Wellcome open research, 9
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Age-dependent acquisition of IgG antibodies to Shigella serotypes-a retrospective analysis of seroprevalence in Kenyan children with implications for infant vaccination.
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Kapulu MC. et al, (2024), Frontiers in immunology, 15
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Bi-isotype immunoglobulins enhance antibody-mediated neutrophil activity against Plasmodium falciparum parasites.
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Ogwang R. et al, (2024), Frontiers in immunology, 15
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A consensus statement on dual purpose pathogen surveillance systems: The always on approach.
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van der Westhuizen H-M. et al, (2024), PLOS global public health, 4
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Rapid identification of bacterial isolates using microfluidic adaptive channels and multiplexed fluorescence microscopy
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Chatzimichail S. et al, (2024), Lab on a Chip, 24, 4843 - 4858
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Epidemiology and microbiology of recurrent UTI in women in the community in Oxfordshire, UK
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Vazquez-Montes MDLA. et al, (2023), JAC-Antimicrobial Resistance, 6
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Discordance between different bioinformatic methods for identifying resistance genes from short-read genomic data, with a focus on Escherichia coli
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Davies TJ. et al, (2023), Microbial Genomics, 9
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Model-based evaluation of admission screening strategies for the detection and control of carbapenemase-producing Enterobacterales in the English hospital setting
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Pople D. et al, (2023), BMC Medicine, 21
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A new variant of the colistin resistance gene MCR-1 with co-resistance to β-lactam antibiotics reveals a potential novel antimicrobial peptide.
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Liang L. et al, (2023), PLoS biology, 21
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Hostile: accurate decontamination of microbial host sequences.
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Constantinides B. et al, (2023), Bioinformatics (Oxford, England), 39
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Global blood miRNA profiling unravels early signatures of immunogenicity of Ebola vaccine rVSVΔG-ZEBOV-GP
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Vianello E. et al, (2023), iScience, 26, 108574 - 108574
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Antibody responses to recombinant vesicular stomatitis virus-Zaire Ebolavirus vaccination for Ebola virus disease across doses and continents: 5-year durability.
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Huttner A. et al, (2023), Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 29, 1587 - 1594
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Erratum: Comparison of R9.4.1/Kit10 and R10/Kit12 Oxford Nanopore flowcells and chemistries in bacterial genome reconstruction
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Sanderson ND. et al, (2023), Microbial Genomics, 9
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Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial
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Hamaluba M. et al, (2023), Wellcome Open Research, 8, 182 - 182
