Researcher of the Month: Dr. Heidi Zinecker
How did you get interested in your scientific work? Although I did not experiment in my own little laboratory in the garage, biology was already one of my favourite subjects at school leading eventually to my decision to study chemistry and biochemistry.
I completed my PhD in the field of innate immunity in plants investigating early elements of plant defense such as the production of reactive oxygen species. To interrogate how the human immune system recognizes and elicits an immune response against pathogens such as viruses, bacteria or parasites is a fascinating research area. In our group we investigate the role of the NOD2 receptor for the development of Crohn’s disease, a chronic inflammation of the digestive tract. By means of our findings we will define novel drug targets in IBD.
Q: What are you working on now?
During the last years I have been working in the field of drug discovery developing bioassays and performing the screening of focused small molecule compound or siRNA libraries. Currently I am working on a drug screening project to identify compounds that modulate immune functions including autophagy, bacterial handling and antigen presentation which might be defective in Crohn’s disease patients.
Q: What do you enjoy the most about working in science?
I have almost always appreciated the challenging and demanding work in the lab. Here at Oxford University I very much enjoy working in such a diverse and excellent scientific environment. A big thanks to all of my colleagues!
The translational aspect of my work is an utterly rewarding and a driving aspect of doing research in the field of immunology. With our findings we hope to improve the treatment and management of a disease that affects the life and welfare of millions of people worldwide.
News & Events
- Blenheim Fun Run 2017
- Curiosity Carnival
- International Clinical Trials Day, May 20th 2017
- The TGU welcomes STEM Apprentice Placements this summer!
- Oxford IBD MasterClass 2017
- Oxford IBD Masterclass 2016
- TGU at the Oxfordshire Science Festival
- A word from Prof. Paul Klenerman, the new Sidney Truelove Professor of Gastroenterology
- TGU at the BBSRC Great British Bioscience Festival
- Members of the Powrie group publish in Nature an important new role of IL-33
- NDM Scientists at Royal Society summer exhibition
- TGU at the Royal Society Summer Science Exhibition 2014
- TGU at the Royal Society Summer Exhibition
- BRC3 Gastro RMF Application form
- Clinician-Scientists in the making visit the TGU from the Chinese University of Hong Kong
- Launch event: Human Iron Research at Oxford (HIRO)
- Detailed map of colon cells in health and disease
- New grant to study the role of immune cells in lung regeneration
- NDM's Translational Gastroenterology Unit awarded a CRUK Primer grant of £100,000
- NDM Researchers elected Fellows of the Academy of Medical Sciences
- Oxford IBD Masterclass 2020
- Oxfordshire Research League Tables
- Memorial Service - Professor Satish Keshav
- Open Evening Crohn's and Colitis
- Tackling inflammatory bowel disease
- Human Immune Discovery Initiative (HIDI)
- The Good Doctors Guide: Meet the best doctors for gall bladder and learn the cutting-edge treatments for inflammatory bowel disease
- forCrohn's Heroes 2018
- TGU Awards, Grants and Prizes Sep-Oct 2016
- BRC - How Vital Funding Makes a Difference
- Falk Foundation Symposium - 29-30 Mar 2019
- Dietary Fibre Metabolite Helps Immune System Fight Invasive Bacteria
- Professor Satish Keshav
- High Sheriff Award
- FALK Symposium Poster First Prize Winner!
- TGU@10 - 10 Years Celebration Event!
- OUH Quality Improvement Symposium (QIP)
- TGU, University of Oxford Awarded the IBD Stress Test QuickFire Challenge
- Crohn's and Colitis Open Evening on Tuesday 4th February at 17.30-19.30
- OUH NURSE WINS NATIONAL AWARD
- Crohn's Disease and Ulcerative Colitis - Public Information Event April 2021
- Oxford IBD MasterClass 2022
- The Changing Face of Inflammatory Bowel Disease- Progress in Research and Clinical Care
- Oxford IBD MasterClass 2024 – Personalising care in IBD
- Please join us for our TGU@14 Symposium on Monday 11th September 2023 at St Anne’s College, Oxford.
- Shortlist Announced for Staff Awards
- NIHR Senior Research Fellows Awards
- Translational Gastroenterology Unit – Logo and Name Update
- TGU Biobank/IBD Cohort
- Training Opportunities
- TGU Podcasts
- Links for TGU Members
- Meet the Team
- Oxford IBD MasterClass 2024