Rebecca Powell Doherty
I’m actually mostly interested in autoimmunity more broadly, so my specific interest in gastroenterology centres around Crohn’s disease and ulcerative colitis, with a tangential interest in coeliac disease. I’m quite committed to the path of basic science and mechanistic elucidation, so the translational aspect of my work is largely a bonus.
1. How did you become interested in translational gastroenterology?
I’m actually mostly interested in autoimmunity more broadly, so my specific interest in gastroenterology centres around Crohn’s disease and ulcerative colitis, with a tangential interest in coeliac disease. I’m quite committed to the path of basic science and mechanistic elucidation, so the translational aspect of my work is largely a bonus.
2. What are you currently working on and what importance does your work hold for current patients with gastrointestinal issues?
My work focuses on the correlations of specific molecules known as HLA molecules with a whole host of autoimmune disorders. These molecules, of which there are many thousands of variants in the human population, present antigen to immune cells for downstream T-cell and B-cell activity. In the context of autoimmunity, I query whether the antigens they present (or fail to present) in any way contribute to the occurrence, exacerbation, or progression of active disease.
3. What do you enjoy most about scientific research?
I honestly couldn’t imagine doing anything else. I love the puzzles that research asks us to solve, and getting to the core of how mechanisms work and why things happen is really rewarding.
4. What’s the best part of being an Oxford University TGU member?
The TGU is great community to be part of, as I have access to cutting edge technology, engaging colleagues, and a tremendous biobank of sample resource that allows me to include clinical translational in my mechanistic work.
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News & Events
- Blenheim Fun Run 2017
- Curiosity Carnival
- International Clinical Trials Day, May 20th 2017
- The TGU welcomes STEM Apprentice Placements this summer!
- Oxford IBD MasterClass 2017
- Oxford IBD Masterclass 2016
- TGU at the Oxfordshire Science Festival
- A word from Prof. Paul Klenerman, the new Sidney Truelove Professor of Gastroenterology
- TGU at the BBSRC Great British Bioscience Festival
- Members of the Powrie group publish in Nature an important new role of IL-33
- NDM Scientists at Royal Society summer exhibition
- TGU at the Royal Society Summer Science Exhibition 2014
- TGU at the Royal Society Summer Exhibition
- BRC3 Gastro RMF Application form
- Clinician-Scientists in the making visit the TGU from the Chinese University of Hong Kong
- Launch event: Human Iron Research at Oxford (HIRO)
- Detailed map of colon cells in health and disease
- New grant to study the role of immune cells in lung regeneration
- NDM's Translational Gastroenterology Unit awarded a CRUK Primer grant of £100,000
- NDM Researchers elected Fellows of the Academy of Medical Sciences
- Oxford IBD Masterclass 2020
- Oxfordshire Research League Tables
- Memorial Service - Professor Satish Keshav
- Open Evening Crohn's and Colitis
- Tackling inflammatory bowel disease
- Human Immune Discovery Initiative (HIDI)
- The Good Doctors Guide: Meet the best doctors for gall bladder and learn the cutting-edge treatments for inflammatory bowel disease
- forCrohn's Heroes 2018
- TGU Awards, Grants and Prizes Sep-Oct 2016
- BRC - How Vital Funding Makes a Difference
- Falk Foundation Symposium - 29-30 Mar 2019
- Dietary Fibre Metabolite Helps Immune System Fight Invasive Bacteria
- Professor Satish Keshav
- High Sheriff Award
- FALK Symposium Poster First Prize Winner!
- TGU@10 - 10 Years Celebration Event!
- OUH Quality Improvement Symposium (QIP)
- TGU, University of Oxford Awarded the IBD Stress Test QuickFire Challenge
- Crohn's and Colitis Open Evening on Tuesday 4th February at 17.30-19.30
- OUH NURSE WINS NATIONAL AWARD
- Crohn's Disease and Ulcerative Colitis - Public Information Event April 2021
- Oxford IBD MasterClass 2022
- The Changing Face of Inflammatory Bowel Disease- Progress in Research and Clinical Care
- Oxford IBD MasterClass 2024 – Personalising care in IBD
- Please join us for our TGU@14 Symposium on Monday 11th September 2023 at St Anne’s College, Oxford.
- Shortlist Announced for Staff Awards
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