I am fascinated by epigenetics and the role the environment plays on the development of disease.
How did you become interested in translational gastroenterology?
I am fascinated by epigenetics and the role the environment plays on the development of disease. Exploring this concept in Crohn’s disease and ulcerative colitis is intriguing due to the mediating role the gene-environment plays in these diseases.
What are you currently working on and what importance does your work hold for current patients with gastrointestinal issues?
I am currently working on a rapid assay using Oxford Nanopore technologies – this has the capacity to aid diagnosis of IBD patients. The rapid test encompasses both underlying genetic mutations and methylation alterations which are biomarkers for diagnosis, disease aggressiveness and treatment response. I am also working on other projects such as understanding the role passive smoking exposure may play on the development of paediatric IBD patients. I am also very interested in the epigenetic clock and assessing if age acceleration is a consequence of Crohn’s disease. We are fortunate that these projects have been supported by the Action Medical Research.
What do you enjoy most about scientific research?
My favourite part of scientific research is exploring our findings to build a picture of how certain areas of the methylome are contributing to disease. I find this side of research truly exhilarating and it only motivates me to continue investigating.
What’s the best part of being an Oxford University TGU member?
The TGU is a great place to carry out scientific research, we are surrounded by experts in a range of fields so there is always the opportunity to upskill and collaborate. The TGU is also a very supportive environment and I am grateful to be a part of this community.
News & Events
- Blenheim Fun Run 2017
- Curiosity Carnival
- International Clinical Trials Day, May 20th 2017
- The TGU welcomes STEM Apprentice Placements this summer!
- Oxford IBD MasterClass 2017
- Oxford IBD Masterclass 2016
- TGU at the Oxfordshire Science Festival
- A word from Prof. Paul Klenerman, the new Sidney Truelove Professor of Gastroenterology
- TGU at the BBSRC Great British Bioscience Festival
- Members of the Powrie group publish in Nature an important new role of IL-33
- NDM Scientists at Royal Society summer exhibition
- TGU at the Royal Society Summer Science Exhibition 2014
- TGU at the Royal Society Summer Exhibition
- BRC3 Gastro RMF Application form
- Clinician-Scientists in the making visit the TGU from the Chinese University of Hong Kong
- Launch event: Human Iron Research at Oxford (HIRO)
- Detailed map of colon cells in health and disease
- New grant to study the role of immune cells in lung regeneration
- NDM's Translational Gastroenterology Unit awarded a CRUK Primer grant of £100,000
- NDM Researchers elected Fellows of the Academy of Medical Sciences
- Oxford IBD Masterclass 2020
- Oxfordshire Research League Tables
- Memorial Service - Professor Satish Keshav
- Open Evening Crohn's and Colitis
- Tackling inflammatory bowel disease
- Human Immune Discovery Initiative (HIDI)
- The Good Doctors Guide: Meet the best doctors for gall bladder and learn the cutting-edge treatments for inflammatory bowel disease
- forCrohn's Heroes 2018
- TGU Awards, Grants and Prizes Sep-Oct 2016
- BRC - How Vital Funding Makes a Difference
- Falk Foundation Symposium - 29-30 Mar 2019
- Dietary Fibre Metabolite Helps Immune System Fight Invasive Bacteria
- Professor Satish Keshav
- High Sheriff Award
- FALK Symposium Poster First Prize Winner!
- TGU@10 - 10 Years Celebration Event!
- OUH Quality Improvement Symposium (QIP)
- TGU, University of Oxford Awarded the IBD Stress Test QuickFire Challenge
- Crohn's and Colitis Open Evening on Tuesday 4th February at 17.30-19.30
- OUH NURSE WINS NATIONAL AWARD
- Crohn's Disease and Ulcerative Colitis - Public Information Event April 2021
- Oxford IBD MasterClass 2022
- The Changing Face of Inflammatory Bowel Disease- Progress in Research and Clinical Care
- Oxford IBD MasterClass 2024 – Personalising care in IBD
- Please join us for our TGU@14 Symposium on Monday 11th September 2023 at St Anne’s College, Oxford.
- Shortlist Announced for Staff Awards
- TGU Biobank/IBD Cohort
- Training Opportunities
- TGU Podcasts
- Links for TGU Members
- Meet the Team
- Oxford IBD MasterClass 2024