About the TGU
The Translational Gastroenterology Unit hosts teams of scientists and clinicians working together to tackle major diseases affecting the gut and the liver. This includes cancers, infections and inflammatory diseases. A longstanding interest of the unit is inflammatory bowel disease (ulcerative colitis and Crohn’s disease), dating back to the era of Sidney Truelove, who developed the first trials and treatments. Together we are now pursuing studies of vaccines, diagnostics, biomarkers, genetics and new clinical interventions in a range of diseases including celiac disease, intestinal failure and auto-immune liver diseases. The unit hosts the Sidney Truelove chair and the Lee Placito chair and around 15 PIs across the different university sites who study various aspects of GI disease at the interface of clinical medicine and basic science. It also hosts a core Flow Cytometry Facility that offers a high-quality Flow Cytometry service to a variety of users. The TGU and flow cytometry facility are supported by the Biomedical Research Centre and Human Immune Discovery Initiative.
ReadItAndKeep: rapid decontamination of SARS-CoV-2 sequencing reads
Hunt M. et al, (2022), Bioinformatics
COVID-19-related changes in outpatient CPAP setup pathways for OSA are linked with decreased 30-day CPAP usage.
Turnbull CD. et al, (2022), Thorax
News and Events
3 May 2022
A new National Institute for Health and Care Research (NIHR) BioResource aimed at investigating inflammatory bowel disease (IBD) in children has opened, with the NIHR Oxford BRC playing a key role.
4 April 2022
The Oxford Bone Infection Research Group NDMOxford is recruiting patients into a new clinical trial for patients with chronic low back pain. To find out more visit http://lowbackpainstudy.co.uk
Featured TGU Researcher
I’m actually mostly interested in autoimmunity more broadly, so my specific interest in gastroenterology centres around Crohn’s disease and ulcerative colitis, with a tangential interest in coeliac disease. I’m quite committed to the path of basic science and mechanistic elucidation, so the translational aspect of my work is largely a bonus.