Modernising Medical Microbiology
Modernising Medical Microbiology is a research group aiming to transform how we analyse and treat infections, to improve patient care.
We aim to:
1) Modernise the way we analyse infections, bringing cutting-edge scientific techniques to clinical care.
2) Transform they way we study the treatment of patients with infections, using large databases of hospital electronic information, to identify trends in how infections are behaving, and ways patient care can be improved.
3) Use techniques such as DNA analysis of bacteria and viruses to better understand how infections spread, how to treat them, and how to prevent them in the future.
4) Study how bacteria become resistant to antibiotics, and more difficult to treat, and how to prevent this.
and how to prevent this.
Modernising Medical Microbiology studies a number of infections, in particular, Mycobacterium tuberculosis (TB), - the Enterobacterales family (Escherichia coli, Klebsiella species and others) and Clostridium difficile (C. diff).
You can learn more about these bacteria here
The Modernising Medical Microbiology Research Group has many active research projects.
You can learn more about the projects here.
If you are interested in being a part of our public engagement team, please get in contact!
Pathogens and viruses
What Pathogens and Viruses do the MMM team research?
M. tuberculosis microvariation is common and is associated with transmission: Analysis of three years prospective universal sequencing in England
Wyllie D. et al, (2022), Journal of Infection, 85, 31 - 39
SARS-CoV-2 antibody trajectories after a single COVID-19 vaccination with and without prior infection.
Wei J. et al, (2022), Nat Commun, 13
Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum.
Tuekprakhon A. et al, (2022), Cell
Potent cross-reactive antibodies following Omicron breakthrough in vaccinees.
Nutalai R. et al, (2022), Cell, 185, 2116 - 2131.e18
Kevin Chau, a PhD student on our National PhD Training Programme in AMR Research, has contributed to the pandemic response as part of the Modernising Medical Microbiology team at John Radcliffe Hospital in Oxford. In a new blog post, he describes the experience.