Prof Timothy SC Hinks
Contact information
+44 1865 (2)20885
Rachel Russell-Sharp
rachel.russell-sharp@ndm.ox.ac.uk
https://orcid.org/0000-0003-0699-2373
Room 7400A, Level 7 NDM, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK
Research groups
The Oxford severe asthma MDT and research nurse team
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Prof Timothy SC Hinks
BMBCh MA (Cantab) MRCP PhD
Wellcome Trust Fellow & Honorary Consultant
- Associate Professor and Wellcome Trust Career Development Fellow, Respiratory Immunology, Nuffield Dept of Medicine
- NIHR Oxford Biomedical Research Centre Senior Research Fellow
- Honorary Consultant, Oxford Special Airway Service, Respiratory Medicine, Oxford University Hospitals NHS Trust
Investigating immune responses in asthma and lung infections
Research Interests
My group investigate the immunopathogenesis of airway diseases and pulmonary infections. We have a specific focus on the roles of novel T cell subsets in the mucosal immunology of the airways, particularly in driving inflammation in asthma and during chronic airways infection.
After a background in translational research in T cell immunodiagnostics in tuberculosis I have been funded by fellowships from the Wellcome Trust, Academy of Medical Sciences and National Institute of Health Research to study novel T cell subsets in the airways in human asthma and more recently the roles of mucosal associated invariant T (MAIT) cells in ex vivo and murine models of infection with Haemophilus influenzae, Legionella and Influenza virus.
Our goal is to better understand the immune responses which protect us from lung infections or can drive airways inflammation, to help develop new treatments to prevent exacerbations of lung diseases and to accelerate the development of improved vaccines.
Funding
Research groups
Innate T cells in airways disease
Airway epithelial cell biology
Websites
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Volunteer as a research participant
If you would be interested in volunteering in our research studies, either as a healthy control or as someone with asthma, fill in this form and we can tell you more
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Bronchoscopy procedure
Watch research volunteer Tom undergo a bronschoscopy
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The ATOMIC2 Trial
The HinksLab are leading this clinical trial of azithromycin in COVID-19
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Severely asthma - Peter's story
Listen to Peter's experience of living with severe asthma, and the transformative effects of new treatments
Recent publications
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Sub‐stratification of type‐2 high airway disease for therapeutic decision‐making: A ‘bomb’ (blood eosinophils) meets ‘magnet’ (
FeNO
) framework
Journal article
Couillard S. et al, (2022), Respirology
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Identifying Bacterial Airways Infection in Stable Severe Asthma Using Oxford Nanopore Sequencing Technologies
Journal article
Jabeen MF. et al, (2022), Microbiology Spectrum, 10
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An ACAT inhibitor regulates SARS-CoV-2 replication and antiviral T cell activity
Schmidt NM. et al, (2022)
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The bacteriology of pleural infection (TORPIDS): an exploratory metagenomics analysis through next generation sequencing.
Journal article
Kanellakis NI. et al, (2022), The Lancet. Microbe, 3, e294 - e302
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Predicting the benefits of type-2 targeted anti-inflammatory treatment with the prototype OxfoRd Asthma attaCk risk scaLE (ORACLE)
Journal article
Couillard S. et al, (2022), ERJ Open Research, 00570 - 2021