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Research groups

Lucy Garner

DPhil Student

Brief biography:

I completed my undergraduate degree in Natural Sciences at the University of Cambridge, specialising in cell and molecular biology.  During this time, I undertook a number of short research projects, including in the lab of Dr Howard Baylis, where I explored novel genetic modifiers of Alzheimer’s disease, and in the lab of Dr Lisa Westerberg at the Karolinska Institutet, where I investigated the function of NK cells in patients with the immunodeficiency disorder Wiskott-Aldrich syndrome.  It was this research experience at the Karolinska Institutet that sparked my interest in immunology and I have pursued this passion ever since. 

Upon completion of my undergraduate degree, I worked as a Research Assistant in Professor Richard Cornall’s group at the University of Oxford (2013-2015), studying models of immunodeficiency disease and a novel class of “superagonistic” antibodies with therapeutic potential.  In 2015, I was awarded a place on the Wellcome Trust Infection, Immunology, and Translational Medicine PhD programme and I am currently completing my DPhil research in Professor Paul Klenerman’s group.

Research interests:

Unconventional T cell populations, mucosal immunity.

Current project:

Mucosal-associated invariant T (MAIT) cells are a novel population of innate-like T cells with anti-bacterial and anti-viral properties.  During my PhD, I am exploring the role of these cells in varied human tissues, including in the gut and liver.  I am particularly interested in the transcriptional regulation of MAIT cell function and how this may be altered in inflammatory disease, for example inflammatory bowel disease.

Publications:

  1. Llibre A, Garner L, Partridge A et al. Expression of lectin-like transcript-1 in human tissues [version 1; referees: 1 approved, 2 approved with reservations]. F1000Research 2016, 5:2929 (doi: 10.12688/f1000research.10009.1)

ResearchGate Profile