Prof Timothy SC Hinks
The Oxford severe asthma MDT and research nurse team
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Prof Timothy SC Hinks
BMBCh MA (Cantab) MRCP PhD
Wellcome Trust Fellow & Honorary Consultant
- Associate Professor and Wellcome Trust Career Development Fellow, Respiratory Immunology, Nuffield Dept of Medicine
- NIHR Oxford Biomedical Research Centre Senior Research Fellow
- Honorary Consultant, Oxford Special Airway Service, Respiratory Medicine, Oxford University Hospitals NHS Trust
Investigating immune responses in asthma and lung infections
My group investigate the immunopathogenesis of airway diseases and pulmonary infections. We have a specific focus on the roles of novel T cell subsets in the mucosal immunology of the airways, particularly in driving inflammation in asthma and during chronic airways infection.
After a background in translational research in T cell immunodiagnostics in tuberculosis I have been funded by fellowships from the Wellcome Trust, Academy of Medical Sciences and National Institute of Health Research to study novel T cell subsets in the airways in human asthma and more recently the roles of mucosal associated invariant T (MAIT) cells in ex vivo and murine models of infection with Haemophilus influenzae, Legionella and Influenza virus.
Our goal is to better understand the immune responses which protect us from lung infections or can drive airways inflammation, to help develop new treatments to prevent exacerbations of lung diseases and to accelerate the development of improved vaccines.
Currently we have a position open for a postdoc - focusing on defining the mechanisms by which bacteria subvert mucosal immunity to establish a niche within the airways. If you are interested, please get in touch by email to find out more.
Innate T cells in airways disease
Airway epithelial cell biology
Recovery of Breakthrough Asthma Attacks Treated With Oral Steroids While on Monoclonal Antibody Therapy: Protocol for a Prospective Observational Study (BOOST)
Howell I. et al, (2023), JMIR Research Protocols, 12, e46741 - e46741
Epithelial immune activation and intracellular invasion by non-typeable Haemophilus influenzae
Brown MA. et al, (2023), Frontiers in Cellular and Infection Microbiology, 13
Recovery of Breakthrough Asthma Attacks Treated With Oral Steroids While on Monoclonal Antibody Therapy: Protocol for a Prospective Observational Study (BOOST) (Preprint)
Howell I. et al, (2023)
Sub‐stratification of type‐2 high airway disease for therapeutic decision‐making: A ‘bomb’ (blood eosinophils) meets ‘magnet’ (
Couillard S. et al, (2022), Respirology, 27, 573 - 577
Longitudinal changes in sputum and blood inflammatory mediators during FeNO suppression testing.
Couillard S. et al, (2022), Thorax