Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.
IONOEStudyLogo.png

A Multi-centre Prospective Study to Improve Outcomes of Necrotising Otitis Externa in the UK

Status:  In set-up

Opening:  July/August 2021

Target:  >800

Registration: TBC

Funding:  Dunhill Medical Trust; Mason Medical Trust

Necrotising Otitis Externa (NOE) is a severe ear infection which invades the ear canal and reaches the base of the skull. It can affect people with diabetes or poor immune systems, but it most commonly affects elderly patients. In the worst cases, NOE can lead to permanent paralysis of part of the face or long term problems with swallowing. NOE used to be a rare condition, but the number of cases has increased recently; we do not know why. Furthermore, there are no national or international guidelines for the diagnosis or treatment of this disease. This means that there is wide variability in how NOE is treated across the UK and the best strategy is not known.

To ensure that patients receive optimal care, we are keeping records of how and where NOE is diagnosed and treated, and which treatments are successful. We will use this information to investigate what the risk factors are for NOE, if scans and surgical samples are the best way to diagnose this disease, and which type and dose of antibiotics work best.

A network of more than 80 doctors across the UK are helping with this study. In conjunction with the National Infection Trainee Collaborative for Audit and Research (NITCAR), the UK NOE Collaborative is the first group of specialists to work together on this disease.

 

Main Contact: susanne.hodgson@spc.ox.ac.uk