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Papers and Publications

 

Publications

Why do hospital prescribers continue antibiotics when it is safe to stop? Results of a choice experiment survey. Roope LSJ, Buchanan J, Morrell L, Pouwels KB, Sivyer K, Mowbray F, Abel L, Cross ELA, Yardley L, Peto T, Walker AS, Llewelyn MJ, Wordsworth S. BMC Med. 2020 Jul 30;18(1):196. doi:10.1186/s12916-020-01660-4. PMID: 32727604; PMCID: PMC7391515. Click here

Patient engagement with antibiotic messaging in secondary care: a qualitative feasibility study of the ‘review & revise’ experience Mowbray F, Sivyer K, Santillo M, Jones N, Peto Tim EA, Walker A. Sarah, Llewelyn MJ, Yardley L. Pilot & Feasibility Studies, 2020 Apr.  Click here

Adaptation and implementation of the ARK (Antibiotic Review Kit) intervention to safely and substantially reduce antibiotic use in hospitals: a feasibility study.  Cross ELA, Sivyer K, Islam J, Santillo M, Mowbray F, Peto TEA, Walker AS, Yardley L, Llewelyn MJ. J Hosp Infect. 2019 Nov Volume 103, Issue 3, Pages 268–275 2019:20(1):421. doi: 10.1186/s13063-019-3497-y. Click here

Antibiotic Review Kit for Hospitals (ARK-Hospital): study protocol for a stepped-wedge cluster-randomised controlled trial. Walker AS, Budgell E, Laskawiec-Szkonter M, Sivyer K, Wordsworth S, Quaddy J, Santillo M, Krusche A, Roope L, Bright N, Mowbray F, Jones N, Hand K, Ra hman N, Dobson M, Hedley E, Crook D, Sharland M, Roseveare C, Hobbs R, Butler C, Vaughan L, Hopkins S, Yardley L*, Peto TEA*, Llewelyn MJ* on behalf of the ARK trial team. Trials 2019:20(1):421. doi: https://doi.org/10.1016/j.jhin.2019.07.017. Click here

The antibiotic course has had its day. Llewelyn MJ, Fitzpatrick J, Darwin E, Tonkin-Crine S, Gorton C, Paul J, Peto T, Yardley L, Hopkins S, Walker AS. BMJ 2017; 358 doi: https://doi.org/10.1136/bmj.j3418. 259.  click here

A national quality incentive scheme to reduce antibiotic overuse in hospitals: evaluation of perceptions and impact. Islam J, Ashiru-Oredope D, Budd E, Howard P, Walker AS, Hopkins S, Llewelyn MJ. Journal of Antimicrobial Chemotherapy. 2018. Jun 1;73(6):1708-1713. doi: 10.1093/jac/dky041.  Click here

Overview of systematic reviews assessing the evidence for shorter versus longer duration antibiotic treatment for bacterial infections in secondary care. Onakpoya IJ, Walker AS, Tan PS, Spencer EA, Gbinigie OA, Cook J, Llewelyn MJ, Butler CC. PLoS One. 2018 Mar 28;13(3):e0194858. doi: 10.1371/journal.pone.0194858. Click here

It’s time to put a hard stop to antibiotic overprescribing in hospitals. Llewelyn MJ, Nagg S, Garcia-Arias V and Jones N. BMJ Opinion, March 2019. Click here

Intervention planning for Antibiotic Review Kit (ARK): a digital and behavioural intervention to safely review and reduce antibiotic prescriptions in acute and general medicine. Santillo M, Sivyer K, Krusche A, Mowbray F, Jones N, Peto TEA, Walker AS, Llewelyn MJ, Yardley L, ARK-Hospital. Journal of Antimicrobial Chemotherapy. 2019 Aug 20. pii: dkz333. doi: 10.1093/jac/dkz333. Click here

 

Presentations

ARK - Feasibility of a complex behaviour change intervention in secondary care to safely and substantially reduce antibiotic use. Presentation by Elizabeth Cross at the FIS conference November 2017. FIS ARK-Hospital

Antibiotic Review Kit - Hospital (ARK-hospital). Presentation by Elizabeth Cross at the Society for Acute Medicine Autumn conference September 2017. ARK-Hospital SAM talk 07_09_17

Poster Presentation at ECCMID 2017.  Budgell EP, Davies T, Llewelyn M, Wylie D, Peto T, Gill MJ, Walker AS. Are shorter antibiotic courses associated with increased mortality or readmission risk in acute/general medicine inpatients?  click here

 

In this section

The Bio-medical Research Council (BRC), a part of the Oxford Hospital Radcliffe Trust (OHRT), funds research and many of our staff are involved in BRC research.

Our research is funded from a variety of funders. Their support allows our research to focus on the basic and clinical research domains to accelerate knowledge translation from the bedside to the bench, and back again.