Improved performance predicting clarithromycin resistance in Mycobacterium abscessus on an independent dataset.
Lipworth S., Hough N., Buchanan R., Smith EG., Robinson E., Alexander E., Peto T., Crook D., Walker T.
In our recent study of 203 sequential isolates evaluating the ability of whole genome sequencing (WGS) to predict clarithromycin resistance in Mycobacterium abscessus (M. abscessus) (1), we demonstrated high sensitivity but poor specificity of mutations identified in a literature search. ….