Our main research focus is hepatitis B virus; we are investigating different outcomes of infection, and are particularly interested in understanding why and how some people's immune systems can control and clear the virus, while others develop life-long infection. In the long term, this will help us find the best ways to design new treatment.
Oxford University joined with researchers and academics in cities across Europe to host Curiosity Carnival as part of 'European Researchers Night'. A huge variety of events was held in Oxford, with museums, galleries and gardens open to the public to meet and engage with research teams working on a wide variety of topics.
Our team was based at the Ashmolean Museum; we used the theme of viruses changing, evolving and spreading to inspire artwork and modelling. A computer game allowed participants to try to copy the genetic code of a virus. If you'd like to have a go, click here!Here's Anna show-casing all the model viruses that were made by Curiosity Carnival participants
World Hepatitis Day aims to stimulate interest and discussion about viral hepatitis infections, creating more awareness, and helping move towards global targets for eliminating this group of diseases.
Our team of doctors, nurses, research scientists and patient advocates had a stand at the John Radcliffe Hospital on 28th July: we used posters, leaflets, stickers and creative activities to stimulate discussion about viral hepatitis. We were also featured on a local Oxford radio station, JackFM, talking about the need for more education around these infections, especially in schools.
World Hepatitis Day is an opportunity to celebrate some of the huge advances that have been made in the treatment and prevention of viral hepatitis infections.
However, we also need to increase awareness - we know that over 300 million people are living with these infections, and the majority of these don't know they have the infection. Many patients around the world can't access the treatment they need, and we still need to work hard to tackle the stigma and discrimination that can be attached to these infections.
We are involved in activities, events and workshops in hospitals and schools throughout the year.
The term ‘footprints’ has been used in science to reflect the changes that can be seen in viruses as they alter to evade our immune system (click on this link if you want to know more).
In this project, we are using the idea of footprints in a broader sense, to stimulate thought and creativity around the numerous dynamic ways that we interact with viruses.
The footprint theme is also a way to explore the impact that infection can have on us, which might be an effect on a whole population, or the unique journey and experiences of one individual person.
For patients in hospital, the theme is expanded to encourage thinking around the way we might leave 'footprints' through our interactions with others and the marks we make on the world.
Among school students, we are exploring the footprints theme to encompass ideas ranging from a world view that considers the way that footprints of human travel can impact on the spread of infections, down to molecular interactions through which human and pathogen leave their marks on one another.
Working with people in hospital, we are using the beauty and intrigue of viruses to stimulate interest and creativity, using a variety of images to inspire activities ranging from design to origami. The focus and concentration required for these tasks can provide a welcome respite from the anxiety and boredom that patients in hospital often suffer.
Asking participants to design and send a postcard inspired by the project will allow us to develop our own network of international ‘footprints’.
As well as the selection of images shown on this page, you can find more of our output by clicking on the links listed at the bottom of this page.
At Rose Hill Primary School, children from years 2 and 6 created beautiful artwork to show the beauty and intrigue of viruses.
Discussing how we protect ourselves from infections... with Year 10 students from Cheney School.
'I have learnt that white bloods cells fight germs' (Year 2 pupil, Rose Hill Primary School).
We made our own viruses, and learnt about how our amazing bodies fight infections.
Why do I care about pathology?
We discussed how pathology incorporates themes from art, medicine, geography, anthropology, history, and maths, using real examples of understanding infection at a workshop at the School of St Helen and St Katherine, Oxford.
'I learnt that there are different ways to be a scientist' [GCSE student, School of St Helen and St Katherine]
'It's useful to know more about a branch in medicine that could be a potential choice of career' [GCSE student, Cheney School]
We are trying to tackle stigma by encouraging open dialogue, providing education, and increasing awareness of hepatitis viruses among patients, healthcare workers and the public.
Our work in collaboration with many centres in Africa, including Uganda, South Africa, Cameroon and Kenya, illustrates the stigma and discrimination that still exists for people with these infections, and for their families. This can be a barrier to getting the right treatment, and to preventing new infections. We hope that our ongoing work will continue to tackle this and identify ways to reduce stigma.
We are developing this work further to link in with projects that seek to alleviate boredom for patients undergoing hospital treatment: to find out more, visit Lizzie's Anti-Boredom Campaign page
We are collecting responses and feedback from everyone who participates in our events, to help to improve the way we communicate messages about sciences and medicine.
An exhibition is planned at the John Radcliffe Hospital in Oxford for December 2017... watch this space!
You can find more of our work on-line by clicking on these links:
Hepatitis B Research Website (this showcases our own research and provides links to our academic output)
Stop-HCV podcasts for World Hepatitis Day 2017 (MRC STOP-HCV group with whom we work closely)
Tropical Medicine Notebook (Oxford University Press 2017) ISBN: 9780198737773
We feature more of our news and activities on twitter, using the twitter handle @pippa_matt or @viralfootprints
You can get in touch directly by email: firstname.lastname@example.org