• Metabolic dysfunction-associated steatotic liver disease
• Hepatic, adipose, and skeletal muscle insulin sensitivity
• Circadian regulation of human metabolism
• Shift-worker health and circadian misalignment
• Sleep-wake abnormalities in patients with liver disease
• Liver involvement during SARS-CoV-2 infection

• British Association for the Study of the Liver (BASL) Andy Burroughs Young Investigator of the Year (2022)
• British Society of Gastroenterology (BSG) Young Gastroenterologist of the Year – Clinical and Translational Science (2022)

I am a Gastroenterology and Hepatology Specialist Registrar at Oxford University Hospitals and an NIHR Academic Clinical Lecturer at the University of Oxford. After graduating from Imperial College London (2012), I have since moved through the integrated academic training pathway as an Academic Clinical Fellow and now Lecturer in Oxford. Over the last 10 years I have developed and applied a range of experimental medicine techniques to decipher the metabolic pathways leading to metabolic dysfunction-associated steatotic liver disease (MASLD). This has included the use of insulin infusion studies, stable isotope assessments of glucose and lipid handling, and analysis of tissue biopsies using multi-omics platforms. More recently, I have developed an interest in circadian regulation of metabolism and during a Wellcome Trust Clinical Research Training Fellowship I completed a DPhil in 2023 which investigated the role of circadian rhythms in the pathogenesis of MASLD. I am currently working on translational human projects relating to diurnal patterns of metabolism, shift-worker health, sleep and glucose control, chronopharmacology, and the assessment of behavioural rhythms using wearable technology. I also have a specialist interest in sleep-wake disturbance in patients with cirrhosis and hepatic encephalopathy. This work spans multiple Oxford departments including the Translational Gastroenterology and Liver Unit (TGLU), the Oxford Centre for Diabetes Endocrinology and Metabolism (OCDEM), and Sir Jules Thorn Sleep and Circadian Neuroscience Institute (SCNi). I have received important mentorship from Professors Jeremy Tomlinson, David Ray, Leanne Hodson, and Ellie Barnes.

I am currently a Young Investigator representative for the European Association for the Study of the Liver (EASL) helping to advance the educational agenda for early career researchers and hepatologists across Europe. I also sit on the EASL Artificial Intelligence Taskforce. From October 2024, I will take up an academic and teaching position at Jesus College Oxford as a Sara Hope Browne Research Associate.