Tamsin Cargill
DPhil student
Brief biography:
I have been working with the Barnes group alongside my clinical training for several years. Much of my work has been focused on translational cellular immunology in immune mediated hepatobiliary disease. Recently I have been awarded a Welcome Trust Clinical Fellowship to undertake a PhD on HBV immunotherapy within the vaccine group.
Research Interests:
I am interested in harnessing cellular immunology to understand disease pathogenesis and develop novel treatment strategies for hepatobiliary conditions.
Current projects:
IgG4-Related Disease Study: Natural history and pathogenesis
Immunotherapy for chronic Hepatitis B infection
Recent publications
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The Differential Complement, Fc and Chemokine Receptor Expression of B Cells in IgG4-Related Pancreatobiliary Disease and Primary Sclerosing Cholangitis and Its Relevance for Targeting B Cell Pathways in Disease.
Journal article
Cargill T. et al, (2024), Biomedicines, 12
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Effect of Prior ChAdOx1 COVID-19 Immunisation on T-Cell Responses to ChAdOx1-HBV.
Journal article
Davis C. et al, (2024), Vaccines, 12
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HBV001: Phase I study evaluating the safety and immunogenicity of the therapeutic vaccine ChAdOx1-HBV.
Journal article
Cargill T. et al, (2023), JHEP reports : innovation in hepatology, 5
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NK cells limit therapeutic vaccine-induced CD8+T cell immunity in a PD-L1-dependent manner.
Journal article
Diniz MO. et al, (2022), Science translational medicine, 14
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Outcomes following SARS-CoV-2 infection in patients with chronic liver disease: An international registry study.
Journal article
Marjot T. et al, (2021), Journal of hepatology, 74, 567 - 577