Research groups
Colleges
Najib M Rahman
BM BCh MA (oxon) MSc (LSHTM) FRCP DPhil
Professor of Respiratory Medicine, Director ORTU
- Director, Oxford Respiratory Trials Unit (ORTU).
- Group Head / PI
- Consultant Physician
- National Speciality Lead, Respiratory Disorders, NIHR CRN
- NIHR Senior Investigator
About me
I am Director of the Oxford Respiratory Trials Unit (ORTU).
My personal research area is pleural disease, for which I received MRC Training Fellowship funding to conduct my DPhil. My group has designed and led multiple multicentre randomised trials in pleural disease which have altered treatment for thousands of patients per year, and appear in national and international guidelines. This includes diagnostics in malignant effusion, treatment of malignant effusion, pleural infection and pneumothorax, and the use of ultrasound and thoracoscopy.
In parallel, I lead the Translational Pleural Laboratory, which utilises clinical samples linked to diagnosis and key clinical outcome data to understand the pathobiology of pleural disease, and identify potential new areas of treatment.
Ongoing Research
Our current programme of research is focussed on
1. Practice changing pragmatic trials in all areas of respiratory medicine through collaborative multicentre phase 3 studies (NIHR and HTA funding).
2. Translational science using pleural fluid and pleural biopsies to delineate underlying pathology, phenotype and treatment targets (funded via the Oxford NIHR BRC).
3. Collaborative work across a number of different academic areas including radiology, oncology, surgery and imaging.
Key publications
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Rahman NM. et al, (2011), New England Journal of Medicine, 365, 518 - 526
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Davies HE. et al, (2012), JAMA, 307, 2383 - 2389
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Rahman NM. et al, (2015), JAMA, 314, 2641 - 2641
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Butler CC. et al, (2023), The Lancet, 401, 281 - 293
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Hallifax RJ. et al, (2020), Lancet (London, England), 396, 39 - 49
Recent publications
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Wong C. et al, (2025), Respiratory research, 26
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Agrawal A. et al, (2024), The European respiratory journal, 64
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Sorino C. et al, (2024), Journal of Clinical Medicine, 13, 6331 - 6331
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Meggyesy AM. et al, (2024), Journal of bronchology & interventional pulmonology, 31
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Iqbal B. et al, (2024), Breathe (Sheffield, England), 20
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Leavy OC. et al, (2024), ERJ open research, 10, 474 - 2024
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Harris V. et al, (2024), The Lancet Infectious Diseases
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Lentz RJ. et al, (2024), CHEST Pulmonary, 2
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Bedawi EO. et al, (2024), American journal of respiratory and critical care medicine, 210, 695 - 696
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Walker S. et al, (2024), The European respiratory journal, 64
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Samat AHA. et al, (2024), International journal of cardiology
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Sundaralingam A. et al, (2024), The European respiratory journal
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Bhatnagar M. et al, (2024), ERJ open research, 10, 662 - 2023
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Panou V. et al, (2024), Expert review of respiratory medicine, 18, 423 - 434
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Blyth KG. et al, (2024), Lancet Respir Med
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Walker S. et al, (2024), The European respiratory journal, 63
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Walker S. et al, (2024), European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 65
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Abel K. et al, (2024), The Lancet Microbe, 5, e500 - e507
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Hamid MHBA. et al, (2024), Nat Immunol
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Corcoran JP. et al, (2024), Diagnostics, 14, 589 - 589