Research groups
Colleges
Najib M Rahman
BM BCh MA (oxon) MSc (LSHTM) FRCP DPhil
Professor of Respiratory Medicine, Director ORTU
- Director, Oxford Respiratory Trials Unit (ORTU).
- Group Head / PI
- Consultant Physician
- National Speciality Lead, Respiratory Disorders, NIHR CRN
- NIHR Senior Investigator
About me
I am Director of the Oxford Respiratory Trials Unit (ORTU).
My personal research area is pleural disease, for which I received MRC Training Fellowship funding to conduct my DPhil. My group has designed and led multiple multicentre randomised trials in pleural disease which have altered treatment for thousands of patients per year, and appear in national and international guidelines. This includes diagnostics in malignant effusion, treatment of malignant effusion, pleural infection and pneumothorax, and the use of ultrasound and thoracoscopy.
In parallel, I lead the Translational Pleural Laboratory, which utilises clinical samples linked to diagnosis and key clinical outcome data to understand the pathobiology of pleural disease, and identify potential new areas of treatment.
Ongoing Research
Our current programme of research is focussed on
1. Practice changing pragmatic trials in all areas of respiratory medicine through collaborative multicentre phase 3 studies (NIHR and HTA funding).
2. Translational science using pleural fluid and pleural biopsies to delineate underlying pathology, phenotype and treatment targets (funded via the Oxford NIHR BRC).
3. Collaborative work across a number of different academic areas including radiology, oncology, surgery and imaging.
Key publications
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Journal article
Rahman NM. et al, (2011), New England Journal of Medicine, 365, 518 - 526
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Journal article
Davies HE. et al, (2012), JAMA, 307, 2383 - 2389
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Journal article
Rahman NM. et al, (2015), JAMA, 314, 2641 - 2641
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Journal article
Butler CC. et al, (2023), The Lancet, 401, 281 - 293
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Journal article
Hallifax RJ. et al, (2020), Lancet (London, England), 396, 39 - 49
Recent publications
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Journal article
Graffen SC. et al, (2025), Journal of Thoracic Disease, 17, 1958 - 1966
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Preprint
Symes R. et al, (2025)
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Journal article
Pereira Catarata MJ. et al, (2025), ERJ open research, 11, 1171 - 2024
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Journal article
Golubic R. et al, (2025), Diabetic Medicine, 42
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Journal article
Wong C. et al, (2025), Respiratory research, 26
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Journal article
Abdulqawi R. et al, (2025), Transplant infectious disease : an official journal of the Transplantation Society
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Journal article
Bhatnagar M. et al, (2025), Clinics in Chest Medicine
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Journal article
Wei J. et al, (2024), Journal of Infection, 89, 106361 - 106361
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Journal article
Agrawal A. et al, (2024), The European respiratory journal, 64
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Journal article
Sorino C. et al, (2024), Journal of Clinical Medicine, 13, 6331 - 6331
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Journal article
Meggyesy AM. et al, (2024), Journal of bronchology & interventional pulmonology, 31
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Journal article
Iqbal B. et al, (2024), Breathe (Sheffield, England), 20
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Journal article
Leavy OC. et al, (2024), ERJ open research, 10, 474 - 2024
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Journal article
Harris V. et al, (2024), The Lancet Infectious Diseases
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Journal article
Lentz RJ. et al, (2024), CHEST Pulmonary, 2
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Journal article
Bedawi EO. et al, (2024), American journal of respiratory and critical care medicine, 210, 695 - 696
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Journal article
Walker S. et al, (2024), The European respiratory journal, 64
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Journal article
Samat AHA. et al, (2024), International journal of cardiology
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Journal article
Sundaralingam A. et al, (2024), The European respiratory journal
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Journal article
Bhatnagar M. et al, (2024), ERJ open research, 10, 662 - 2023