Research groups
Colleges
Najib M Rahman
BM BCh MA (oxon) MSc (LSHTM) FRCP DPhil
Professor of Respiratory Medicine, Director ORTU
- Director, Oxford Respiratory Trials Unit (ORTU).
- Group Head / PI
- Consultant Physician
- National Speciality Lead, Respiratory Disorders, NIHR CRN
- NIHR Senior Investigator
About me
I am Director of the Oxford Respiratory Trials Unit (ORTU).
My personal research area is pleural disease, for which I received MRC Training Fellowship funding to conduct my DPhil. My group has designed and led multiple multicentre randomised trials in pleural disease which have altered treatment for thousands of patients per year, and appear in national and international guidelines. This includes diagnostics in malignant effusion, treatment of malignant effusion, pleural infection and pneumothorax, and the use of ultrasound and thoracoscopy.
In parallel, I lead the Translational Pleural Laboratory, which utilises clinical samples linked to diagnosis and key clinical outcome data to understand the pathobiology of pleural disease, and identify potential new areas of treatment.
Ongoing Research
Our current programme of research is focussed on
1. Practice changing pragmatic trials in all areas of respiratory medicine through collaborative multicentre phase 3 studies (NIHR and HTA funding).
2. Translational science using pleural fluid and pleural biopsies to delineate underlying pathology, phenotype and treatment targets (funded via the Oxford NIHR BRC).
3. Collaborative work across a number of different academic areas including radiology, oncology, surgery and imaging.
Key publications
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Journal article
Rahman NM. et al, (2011), New England Journal of Medicine, 365, 518 - 526
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Journal article
Davies HE. et al, (2012), JAMA, 307, 2383 - 2389
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Journal article
Rahman NM. et al, (2015), JAMA, 314, 2641 - 2641
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Journal article
Butler CC. et al, (2023), The Lancet, 401, 281 - 293
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Hallifax RJ. et al, (2020), Lancet (London, England), 396, 39 - 49
Recent publications
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Journal article
Hamid MHBA. et al, (2024), Nat Immunol
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Corcoran JP. et al, (2024), Diagnostics, 14, 589 - 589
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Price E. et al, (2024), ERJ open research, 10, 10 - 2024
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Guo H. et al, (2024), Seminars in respiratory and critical care medicine
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Journal article
Bedawi EO. and Rahman NM., (2024), The European respiratory journal, 63
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Journal article
Chopra A. et al, (2024), The Lancet. Respiratory medicine, 12, 190 - 192
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Standing JF. et al, (2024), Nature Communications, 15
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Addala DN. and Rahman NM., (2024), Annals of the American Thoracic Society, 21, 202 - 203
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Png ME. et al, (2024), British Journal of General Practice, BJGP.2023.0444 - BJGP.2023.0444
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Carneiro DC. et al, (2024), Clinics, 79, 100356 - 100356
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Gonnelli F. et al, (2024), Respiratory research, 25
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Taquet M. et al, (2023), Brain Communications, 6
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Elneima O. et al, (2023), International Journal of Epidemiology
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Elsheikh A. et al, (2023), Breathe (Sheffield, England), 19
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Pietersen PI. et al, (2023), BMC Pulmonary Medicine, 23
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De Fonseka D. et al, (2023), The European respiratory journal
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Pietersen PI. et al, (2023), Breathe (Sheffield, England), 19
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Journal article
Steen K. et al, (2023), J Thorac Dis, 15, 6323 - 6332
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Rahman N. et al, (2023), Substance use & misuse, 1 - 5
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Brightling CE. et al, (2023), The Lancet Respiratory Medicine, 11, e93 - e94