Contact information
                        
                        
                            
                            michael.fitzpatrick@ndm.ox.ac.uk
                        
                        
                    
                        
                        
                            
                            
                            https://orcid.org/0000-0003-2365-2012
                        
                    
                        
                        
                        Twitter: @DoctorFitz
                    
Michael FitzPatrick
MA (Cantab) MBBS DHMSA MRCP DPhil
Consultant and researcher in Gastroenterology and Nutrition
Biography
I am a consultant gastroenterologist at Oxford University Hospitals and a researcher at the University of Oxford. My research interests include gut immunology and disease, with a particular focus in T cell biology, coeliac disease, and intestinal transplantation. I am overtly fond of the rebellious T cells that break the 'rules' of adaptive immunology: MAIT cells, γδ T cells & tissue resident populations.
My clinical work focuses on luminal gastroenterology, complex nutrition and coeliac disease. I have wider interests in medical education, healthcare policy, and inequalities in health.
I am the co-host (with Tamsin Cargill) of a gastroenterology research podcast, Gut Instinct: GI Research Update.
Recent publications
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                Immune–epithelial–stromal networks define the cellular ecosystem of the small intestine in celiac disease
Journal article
FitzPatrick MEB. et al, (2025), Nature Immunology, 26, 947 - 962
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                Single-cell integration reveals metaplasia in inflammatory gut diseases.
Journal article
Oliver AJ. et al, (2024), Nature, 635, 699 - 707
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                Nutritional care pathways in cancer patients with malignant bowel obstruction: A retrospective multi-centre study.
Journal article
Patel PS. et al, (2024), Clinical nutrition ESPEN, 59, 118 - 125
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                An Interpretable Classification Model Using Gluten-Specific TCR Sequences Shows Diagnostic Potential in Coeliac Disease.
Journal article
Fowler A. et al, (2023), Biomolecules, 13
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                Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity
Journal article
Garner LC. et al, (2023), Nature Immunology, 24, 1565 - 1578
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                A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice
Journal article
Hackstein C-P. et al, (2022), Nature Communications, 13
 
