Contact information
michael.fitzpatrick@ndm.ox.ac.uk
https://orcid.org/0000-0003-2365-2012
Twitter: @DoctorFitz
Michael FitzPatrick
MA (Cantab) MBBS DHMSA MRCP DPhil
Consultant and researcher in Gastroenterology and Nutrition
Biography
I am a consultant gastroenterologist at Oxford University Hospitals and a researcher at the University of Oxford. My research interests include gut immunology and disease, with a particular focus in T cell biology, coeliac disease, and intestinal transplantation. I am overtly fond of the rebellious T cells that break the 'rules' of adaptive immunology: MAIT cells, γδ T cells & tissue resident populations.
My clinical work focuses on luminal gastroenterology, complex nutrition and coeliac disease. I have wider interests in medical education, healthcare policy, and inequalities in health.
I am the co-host (with Tamsin Cargill) of a gastroenterology research podcast, Gut Instinct: GI Research Update.
Recent publications
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Single-cell integration reveals metaplasia in inflammatory gut diseases.
Oliver AJ. et al, (2024), Nature, 635, 699 - 707
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Nutritional care pathways in cancer patients with malignant bowel obstruction: A retrospective multi-centre study.
Patel PS. et al, (2024), Clinical nutrition ESPEN, 59, 118 - 125
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An Interpretable Classification Model Using Gluten-Specific TCR Sequences Shows Diagnostic Potential in Coeliac Disease.
Fowler A. et al, (2023), Biomolecules, 13
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Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity
Garner LC. et al, (2023), Nature Immunology, 24, 1565 - 1578
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A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice
Hackstein C-P. et al, (2022), Nature Communications, 13
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Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon‐, TNF‐, and IL‐18‐dependent manner
Provine NM. et al, (2022), European Journal of Immunology, 52, 835 - 837