Claire Hutchings
Research Assistant
I am a post-doctoral research assistant, supporting Professor Paul Klenerman’s research on immune responses to viral infection, immune memory, and host–pathogen interactions. My role focuses on the practical and regulatory aspects of delivering in vivo research, working closely with researchers to support studies from planning through to delivery.
I provide day-to-day oversight of Professor Klenerman’s animal project licence, which underpins the group’s in vivo work, with a focus on governance, compliance, and good practice. I support personal licence holders by providing training, helping to develop and review study plans, and approving work to ensure it is scientifically robust and meets regulatory requirements.
I am also responsible for amendments and new licence applications, working closely with researchers, technical staff, and governance teams to ensure that the research program runs smoothly while maintaining high standards of animal welfare and scientific quality.
Recent publications
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First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults.
Journal article
Cicconi P. et al, (2020), Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 70, 2073 - 2081
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Use of an Outbred Rat Hepacivirus Challenge Model for Design and Evaluation of Efficacy of Different Immunization Strategies for Hepatitis C Virus.
Journal article
Atcheson E. et al, (2020), Hepatology (Baltimore, Md.), 71, 794 - 807
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Divergent memory responses driven by adenoviral vectors are impacted by epitope competition.
Journal article
Colston JM. et al, (2019), European journal of immunology, 49, 1356 - 1363
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Single-cell transcriptome analysis of CD8+ T-cell memory inflation
Journal article
Highton AJ. et al, (2019), Wellcome Open Research, 4, 78 - 78
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Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults.
Journal article
Green CA. et al, (2019), The Journal of infection, 78, 382 - 392
