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See all our currently recruiting studies below:

Current trials - RECRUITING NOW


1. ABRA STUDY

The use of Benralizumab, an interleukin-5 receptor-α monoclonal antibody as treatment of acute exacerbations of airways disease.

If you are interested in taking part please do not hesitate to contact us on 01865 221771

 

2. CORAL STUDY

A 12-week exploratory study to characterise the relationship between changes in Inflammatory markers, lung function, symptoms and reliever use in Chronic Obstructive Pulmonary Disease Patients.

If you are interested in taking part please do not hesitate to contact us on 01865 221771

 

3. OAS – Oxford Airways Study

An observational study to measure biomarkers, inflammation, and mediators from healthy volunteers and participants with airways disease at stable state and during acute exacerbation. The purpose of this study is to understand more about conditions such as asthma, COPD, bronchiectasis and nasal polyps (conditions we often call ‘airways diseases’). We do not fully understand the mechanisms which cause these airways diseases and performing this research we hope will allow us to design better treatments for patients. We aim to build up a detailed picture of participants’ airways and how they are working.

If you are interested in taking part please do not hesitate to contact us on 01865 221538 or rmu@ndm.ox.ac.uk

 

4. AES - INVESTIGATIONS OF IMMUNE MECHANISMS OF THE AIRWAY EPITHELIUM.

Airway epithelial cells are the building blocks that make up the surface of the airways, known as the epithelium. This study aims to investigate defence mechanisms of these airway epithelial cells from patients with airways diseases. We are particularly interested in discovering why some patients experience prolonged infections while others don’t. In the laboratory we will isolate cells from the samples you gift, and measure their responses when we add bacteria and other stimulants

If you are interested in taking part please do not hesitate to contact us on 01865 221538 or rmu@ndm.ox.ac.uk


5. STIFLE

Investigating Asthma inflammation in patients taking daily Asthma medication. Measurements will be performed daily by patients at home using devices which will connect to a smartphone.

- Are you aged over 18
- Have you been diagnosed with Asthma for longer than 6 months
- Can you complete daily measurements at home for the next 6 months
- Have you needed to use oral steroids for worsening asthma symptoms

If so please contact one of our research team on 01865 221538 or Ouh-tr.stifle@nhs.net


6. TREETOP STUDY

The purpose of this study is to investigate a new type of breathing test using a novel laser gas analyser, which provides new measures of lung function.

In particular the study aims to investigate the effect of smoking on these new measures of lung function. We are looking for current smokers without a diagnosis of any lung disease (e.g. asthma or COPD). For more information please click here.

 

If you are interested in taking part please do not hesitate to contact us:

Email: denise.fleming-brown@ndm.ox.ac.uk, Phone: 07554 436726  or                                                            Email: beverly.langford@ndm.ox.ac.uk, Phone: 07769 280289

 


7. OPTIMAN - The use of exhaled nitric oxide to manage asthma in primary care

The OPTIMAN study is designed to demonstrate how we can use a chemical that is measurable in the breath to better give treatments for asthma. The OPTIMAN study aims to do this for both those who have already been diagnosed and treated for asthma and for those who are coming to see their GP for the very first time with symptoms of asthma. We aim to get the diagnosis of asthma correct and then using FeNO to optimise the drug treatment.

If you are interested in taking part please do not hesitate to contact us on 01865 221538