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Populations

Oxford University Lead: Sarah Walker; UKHSA co-lead: Susan Hopkins

We would like to better understand who is affected by antimicrobial resistance and healthcare-associated infections, and why, including the impact of inequalities and aging, and how we can monitor these conditions. Our strategy is to exploit large-scale linked electronic health record (EHR) data from multiple sources to answer the following key questions:

  • How can routine surveillance be automated optimally?
  • What populations are at greatest risk of different healthcare associated infections (HAI) and antimicrobial resistance (AMR)

By automating surveillance using EHR we hope to improve the monitoring and management of infectious diseases, reduce the burden of data collection in the NHS and better predict future trends in antimicrobial usage, HAI and AMR.

 

Populations Theme Publications

Healthcare-associated COVID-19 in England: a national data linkage study

Bhattacharya A, Collin S M, Stimson J, et al.

https://www.medrxiv.org/content/10.1101/2021.02.16.21251625v1

 

SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN)

Hall V J, Foulkes S, Charlett A, et al.

https://linkinghub.elsevier.com/retrieve/pii/S0140-6736(21)00675-9

 

Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers

Lumley S F, O’Donnell D, Stoesser N, et al.

https://www.nejm.org/doi/full/10.1056/NEJMoa2034545

 

The Duration, Dynamics, and Determinants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Responses in Individual Healthcare Workers

Lumley S, Wei J, O’ Donnell D, et al.

https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab004/6064824.

 

 

 

In this section

The Bio-medical Research Council (BRC), a part of the Oxford Hospital Radcliffe Trust (OHRT), funds research and many of our staff are involved in BRC research.

Our research is funded from a variety of funders. Their support allows our research to focus on the basic and clinical research domains to accelerate knowledge translation from the bedside to the bench, and back again.