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In a controlled trial chloramphenicol proved as effective and much cheaper than penicillin for the treatment of group A meningococcal meningitis in Zaria, Nigeria. A short course of five days cured most patients. Adults and older children were soon able to take chloramphenicol by mouth, which reduced the cost and simplified treatment.It is suggested that chloramphenicol is a suitable alternative to sulphonamides for the treatment of meningococcal meningitis in those parts of Africa where the organism is sulphonamide-resistant.

Type

Journal article

Journal

Br Med J

Publication Date

18/08/1973

Volume

3

Pages

379 - 381

Keywords

Administration, Oral, Cerebrospinal Fluid, Child, Child, Preschool, Chloramphenicol, Clinical Trials as Topic, Female, Hemagglutination Tests, Humans, Infant, Injections, Intramuscular, Male, Meningitis, Meningococcal, Neisseria meningitidis, Nigeria, Penicillin Resistance, Penicillins, Sulfonamides