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The South American tropical rattlesnake (Crotalus durissus subspp) is responsible for approximately 10% of bites from venomous snakes in Brazil. We studied 24 victims of bites by this species over 3 years, in south-eastern Brazil, particularly investigating haemostatic alterations. Thirteen patients were defined as moderately envenomed and 11 as severe. There were two deaths, which were not attributed to venom-induced haemostatic disturbances. However, envenoming by C. durissus is frequently associated with haemostatic disorders, which are probably attributable mainly to the action of the thrombin-like enzyme, with possible additional effects secondary to the powerful myotoxic activity of the venom.


Journal article



Publication Date





551 - 559


Adolescent, Adult, Aged, Animals, Antivenins, Blood Coagulation Disorders, Brazil, Child, Crotalid Venoms, Enzyme-Linked Immunosorbent Assay, Female, Humans, Male, Middle Aged, Snake Bites