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Roles of lung volumes in asthma remain controversial. We aimed to evaluate the efficacy of lung volumes in differentiating asthma severity levels. Consecutive outpatients with chronic persistent asthma were enrolled, and body plethysmography (BP) and helium dilution (HD) were performed simultaneously to extract RV%pred, TLC%pred, and RV/TLC. Significant negative correlations were found between FEV1%pred and RV%pred (r = -0.557, P 1 in identifying asthma severity levels.

Original publication




Journal article


Scientific reports

Publication Date





Department of Respiratory Diseases, West China School of Medicine and West China Hospital, Sichuan University, Chengdu, China.


Lung, Humans, Asthma, Helium, Plethysmography, Respiratory Function Tests, Forced Expiratory Volume, Severity of Illness Index, Area Under Curve, ROC Curve, Adult, Aged, Middle Aged, Female, Male