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CAPSULE SUMMARY: Out of all type-2 immune cells, only ILC2s withstand corticosteroid treatment due to a reduced pro-apoptotic machinery. The findings may advance the understanding on the mechanism in steroid-resistant diseases and facilitate the development of improved therapies.

Original publication




Journal article


J Allergy Clin Immunol

Publication Date



Asthma, Bcl-2, ILC2, Tc2, Th2, apoptosis, corticosteroids, mitochondria