The NIHR Health Protection Research Unit (HPRU) in Healthcare Associated Infections and Antimicrobial Resistance (AMR) is a partnership between Public Health England (PHE) and the University of Oxford in collaboration with University of Leeds, Animal and Plant Health Agency and European Bioinformatics Institute.
National Institute for Health Research (NIHR) has provided funding to establish 14 Health Protection Research Units (HPRU) to address key public health threats. The HPRUs are partnerships between Universities and Public Health England forming multi-disciplinary centres of excellence with a focus on collaborations and knowledge sharing.
HPRU in Healthcare Associated Infections and Antimicrobial Resistance at Oxford University is led by Professor Sarah Walker and our PHE lead is Dr Susan Hopkins.
The HPRU in Healthcare Associated Infections and AMR vision is to find better ways to manage and prevent threats from antimicrobial resistance and healthcare-associated infections, by detecting them faster, working out who needs protecting most and how this can be done.
It consists of 4 broad Research Themes:
NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance
We want to create opportunities for individuals to interact, engage and contribute to our research to: Improve its quality and relevance: Ensure our research questions align with the wider public’s priorities: Disseminate findings to everyone who may find them relevant, useful or interesting: Inspire adults and children and promote careers in research and Science, Technology, Engineering, and Mathematics
Our strategy for knowledge mobilisation/policy-maker engagement is based on PHE leaders being best-placed to ensure HPRU studies directly inform PHE needs and results are disseminated beyond academia, including into PHE guidance/outputs
Therapeutic vaccination for treatment of chronic hepatitis B.
Cargill T. and Barnes E., (2021), Clinical and experimental immunology, 205, 106 - 118
HLA-dependent variation in SARS-CoV-2 CD8+ T cell cross-reactivity with human coronaviruses
Buckley PR. et al, (2021)
BashTheBug: a crowd of volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates.
Fowler PW. et al, (2021)
Estimating the effectiveness of first dose of COVID-19 vaccine against mortality in England: a quasi-experimental study
Bermingham CR. et al, (2021)
13 May 2021
On 29 April 2021 leading clinicians and scientists from the Oxford Translational Gastroenterology Unit will present on the latest research into the causes, treatment and monitoring of Crohn’s and Colitis.
20 October 2020
Two vital research programmes taking place at the University of Oxford may hold the key to understanding the immunity of recovered Covid-19 patients. The data will also be used by Professor Sarah Walker at the University of Oxford who is working with the Office for National Statistics on the COVID-19 Infection Survey.