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We established the COLORS in IBD study (COLitis of early Onset - Rare diseaseS withIN IBD disease phenotypes) to investigate novel genetic effects in early onset intestinal inflammation.  COLORS is a collaboration with the Sanger Center Cambridge and the Wellcome Trust Center of Human Genomics (WTCHG) Oxford.  

colours-in-ibd.pngOur collaboration allows us to investigate patients with pediatric onset of IBD by modern genetic methods and to compare genotypes with functional immune responses. COLORS in IBD also has several international collaborators, increasing our access to patients and patient data.

H Uhlig, Gut 2013

uhlig-2013.jpgUhlig HH. Gut 2013 Monogenic diseases associated with intestinal inflammation: implications for the understanding of inflammatory bowel disease

Uhlig et al. Gastroenterology 2014 The diagnostic approach to monogenic very early onset inflammatory bowel disease.

 

Uhlig HH, Muise AM. Trends Genet. 2017  Clinical Genomics in Inflammatory Bowel Disease.