Sheila Lumley
DPhil student
I am an infectious diseases registrar currently undertaking a Dphil in the Matthews group supported by a Wellcome Trust Clinical Research Training Fellowship.
I have been working with the Matthews group alongside my clinical training since 2015, developing my interest in viral genomics and the application of novel sequencing platforms to clinical practice. I am currently investigating a range of diagnostic platforms, including lateral flow devices, LAMP, and sequencing, for diagnosis of respiratory viruses including SARS-CoV-2.
I am working closely with colleagues at Oxford University Hospitals NHS Foundation Trust to deliver a large scale staff SARS-CoV-2 testing programme (over 12,500 staff tested to date), to provide enhanced infection prevention control and answer critical questions about post-infection immunity.
I continue to contribute to clinical work, and co-ordinate and deliver medical student teaching as a Teaching Fellow at Green Templeton College and as a lecturer for medical school infection teaching programs.
Recent publications
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Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera.
Journal article
Zhou D. et al, (2021), Cell
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Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections.
Journal article
Eyre DW. et al, (2021), BMC Infect Dis, 21
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Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers
Journal article
Lumley SF. et al, (2021), New England Journal of Medicine, 384, 533 - 540
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COVID-19 CT pulmonary angiogram examinations and reported pulmonary embolism incidence: comparison between peak first wave and early second wave.
Journal article
Tsakok MT. et al, (2021), Clin Radiol
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Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera
Journal article
Supasa P. et al, (2021), Cell