Sheila Lumley
DPhil student
I am an infectious diseases registrar currently undertaking a Dphil in the Matthews group supported by a Wellcome Trust Clinical Research Training Fellowship.
I have been working with the Matthews group alongside my clinical training since 2015, developing my interest in viral genomics and the application of novel sequencing platforms to clinical practice. I am currently investigating a range of diagnostic platforms, including lateral flow devices, LAMP, and sequencing, for diagnosis of respiratory viruses including SARS-CoV-2.
I am working closely with colleagues at Oxford University Hospitals NHS Foundation Trust to deliver a large scale staff SARS-CoV-2 testing programme (over 12,500 staff tested to date), to provide enhanced infection prevention control and answer critical questions about post-infection immunity.
I continue to contribute to clinical work, and co-ordinate and deliver medical student teaching as a Teaching Fellow at Green Templeton College and as a lecturer for medical school infection teaching programs.
Recent publications
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Evaluation of sequence hybridization for respiratory viruses using the Twist Bioscience Respiratory Virus Research panel and the OneCodex Respiratory Virus sequence analysis workflow.
Journal article
Kapel N. et al, (2023), Microbial genomics, 9
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Pan-genotypic probe-based enrichment to improve efficiency of Hepatitis B virus sequencing
Preprint
Lumley SF. et al, (2023)
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Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19
Journal article
Kotanidis CP. et al, (2022), The Lancet Digital Health, 4, e705 - e716
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Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses
Journal article
McNaughton AL. et al, (2022), JCI Insight, 7
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A new method to identify co-variation in hepatitis B virus whole genome sequences identifies networks of polymorphisms associated with drug resistance
Conference paper
Lumley S. et al, (2022), JOURNAL OF HEPATOLOGY, 77, S856 - S857