Martin Lett

Dr Martin J. Lett is a Postdoctoral Research Fellow in the Klenerman Laboratory at the University of Oxford, within the Nuffield Department of Medicine. His research focuses on elucidating the relationship between mucosal-associated invariant T (MAIT) cells and the microbiota, with particular emphasis on their antigens, including 5-OP-RU. His interests include developing innovative tools to detect and target molecules of interest in biological matrices.

Martin Lett obtained his PhD in Cell Biology from the University of Basel in 2020, where his doctoral work examined the role of liver cells in bacterial antigen metabolism and MAIT cell activation. He also holds a Doctor of Pharmacy (PharmD) degree from the University of Strasbourg and a Master’s degree in Pharmacology. His earlier research explored the molecular mechanisms underlying cell migration, invasion, and metastasis.

Prior to joining Oxford, he undertook postdoctoral research in molecular virology at the University of Basel, where he contributed to the development of a method to generate recombinant modified SARS-CoV-2 viruses and to COVID-19 vaccine development. Alongside his research, he has been actively involved in teaching and supervision, supporting undergraduate and postgraduate students in immunology and related disciplines.