Contact information
Research groups
Alexandra Noble
Postdoctoral Scientist
Biography
Dr Alexandra Noble is Girdlers’ Health Research Council of New Zealand Fellow at Green Templeton College, University of Oxford.
Alexandra earned her PhD in 2021 from the University of Canterbury, New Zealand, where she focused on the impact of environmental exposures on DNA methylation. Following this, she joined the Translational Gastroenterology Unit at the University of Oxford as a postdoctoral researcher, under the supervision of Professors Jack Satsangi and Holm Uhlig.
Alexandra’s current research centres on long-read genomic sequencing and DNA methylation biomarkers for Inflammatory Bowel Disease (IBD). She aims to translate these biomarkers into a rapid, novel assay using Oxford Nanopore sequencing. This approach seeks to assist clinicians in diagnosing, prognosing, and tailoring drug treatments for patients.
Recent publications
-
Altered DNA methylation within DNMT3A, AHRR, LTA/TNF loci mediates the effect of smoking on inflammatory bowel disease
Journal article
Zhang H. et al, (2024), Nature Communications, 15