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Publications

Virtual alignment of pathology image series for multi-gigapixel whole slide images.

Gatenbee CD. et al, (2023), Nature communications, 14

β-catenin drives butyrophilin-like molecule loss and γδ T-cell exclusion in colon cancer.

Suzuki T. et al, (2023), Cancer immunology research

Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features

Flanagan DJ. et al, (2023), Nature Communications, 14

Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features

Flanagan DJ. et al, (2022), Nature Communications, 13

Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.

Gil Vazquez E. et al, (2022), Cell stem cell, 29

Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells.

Cañellas-Socias A. et al, (2022), Nature, 611, 603 - 613

Homeostasis limits keratinocyte evolution.

Schenck RO. et al, (2022), Proc Natl Acad Sci U S A, 119

The Emerging Era of Personalised Medicine in Advanced Colorectal Cancer.

Wu CW. et al, (2022), Journal of gastroenterology and hepatology

Biological misinterpretation of transcriptional signatures in tumour samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data.

Fisher NC. et al, (2022), Clinical cancer research : an official journal of the American Association for Cancer Research

Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer.

Hashimoto T. et al, (2022), British journal of cancer

Molecular phenotyping of colorectal neoplasia shows dynamic and adaptive cancer stem cell population admixture

Vazquez EG. et al, (2022)

Germline variant testing in serrated polyposis syndrome

Murphy A. et al, (2022), Journal of Gastroenterology and Hepatology, 37, 861 - 869

Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer.

Corry SM. et al, (2022), Gut

Immunosuppressive niche engineering at the onset of human colorectal cancer.

Gatenbee CD. et al, (2022), Nat Commun, 13

Gattaca: Base pair resolution mutation tracking for somatic evolution studies using agent-based models.

Schenck RO. et al, (2022), Molecular biology and evolution

The molecular subtyping resource (MouSR): a user-friendly tool for rapid biological discovery from transcriptional data.

Ahmaderaghi B. et al, (2022), Disease models & mechanisms

Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues

Gabbutt C. et al, (2022), Nature Biotechnology

Patch-Level Instance-Group Discrimination with Pretext-Invariant Learning for Colitis Scoring

Xu Z. et al, (2022), Machine Learning in Medical Imaging, 101 - 110

The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis.

Kobayashi H. et al, (2021), Gastroenterology

Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas

Heino S. et al, (2021), Science Advances, 7

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