IL-5 antagonism reverses priming and activation of eosinophils in severe eosinophilic asthma.
Luo J. et al, (2024), Mucosal immunology, 17, 524 - 536
Neuromedin U promotes human type 2 immune responses.
Ye Y. et al, (2022), Mucosal immunology, 15, 990 - 999
Pre-existing asthma as a comorbidity does not modify cytokine responses and severity of COVID-19
Luo J. et al, (2021), Allergy, Asthma & Clinical Immunology, 17
The Roles of Type 2 Cytotoxic T Cells in Inflammation, Tissue Remodeling, and Prostaglandin (PG) D2 Production Are Attenuated by PGD2 Receptor 2 Antagonism
Chen W. et al, (2021), The Journal of Immunology, 206, 2714 - 2724
Resistance to apoptosis underpins the corticosteroid insensitivity of group 2 innate lymphoid cells.
Luo J. et al, (2019), The Journal of allergy and clinical immunology, 144, 1722 - 1726.e10
Correction: Synergistic activation of pro-inflammatory type-2 CD8 + T lymphocytes by lipid mediators in severe eosinophilic asthma
Hilvering B. et al, (2019), Mucosal Immunology, 12, 581 - 581
FEVIPIPRANT INHIBITS PROSTAGLANDIN D2 MEDIATED ACTIVATION OF GROUP 2 INNATE LYMPHOID CELLS (ILC2S)
Sandham D. et al, (2019), RESPIROLOGY, 24, 105 - 105
Fevipiprant, a Selective Prostaglandin D(2)Receptor 2 Antagonist, Potently Inhibits Chemotaxis and Cytokine Production by Tc2 cells (type-2 CD8(+)lymphocytes)
Xue L. et al, (2019), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 199
Effects of Steroids in Cultured Human Type-2 Cytokine Producing Cells
Luo J. et al, (2018), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 197
The Effect of Oral Corticosteroids on Circulating Type-2 Cytokine Producing Cells in Patients with Severe Eosinophilic Asthma
Hynes G. et al, (2018), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 197
Fevipiprant inhibits prostaglandin D2 mediated activation of group 2 innate lymphoid cells (ILC2s)
Chen W. et al, (2018), EUROPEAN RESPIRATORY JOURNAL, 52
Type-2 CD8+ T lymphocytes responsive to PGD2/LTE4 in severe eosinophilic asthma
Hinks T. et al, (2018), Airway Cell Biology and Immunopathology
Synergistic activation of pro-inflammatory type-2 CD8+ T lymphocytes by lipid mediators in severe eosinophilic asthma
Hilvering B. et al, (2018), Mucosal Immunology, 11, 1408 - 1419
Fevipiprant, a Selective Prostaglandin D-2 Receptor 2 Antagonist, Potently Inhibits Chemotaxis and Cytokine Production by Group 2 Innate Lymphoid Cells
Xue L. et al, (2018), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 197
Cytometric Gating Stringency Impacts Studies of Type 2 Innate Lymphoid Cells in Asthma
Hinks TSC. et al, (2017), American Journal of Respiratory Cell and Molecular Biology, 57, 745 - 747
Cysteinyl leukotriene E 4 activates human group 2 innate lymphoid cells and enhances the effect of prostaglandin D 2 and epithelial cytokines
Salimi M. et al, (2017), Journal of Allergy and Clinical Immunology, 140, 1090 - 1100.e11
Novel data analysis method for multicolour flow cytometry links variability of multiple markers on single cells to a clinical phenotype.
Tinnevelt GH. et al, (2017), Scientific Reports, 7, 5471 - 5471
Sputum Il-17a Levels Correlate With Biomarkers Of Non-Eosinophilic Inflammation In Patients With Asthma
Hynes G. et al, (2017), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 195
Interaction Of Type 2 Cytotoxic T Lymphocytes And Mast Cell Lipid Mediators Contributes To Pathogenesis Of Eosinophilic Asthma
Xue L. et al, (2017), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 195
Type 2 Cytotoxic T Lymphocytes In Patients With Severe Eosinophilic Asthma
Xue L. et al, (2017), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 195