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Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice

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Wang L. et al, (2021), Nature Genetics, 53, 500 - 510

A variant in IL6ST with a selective IL-11 signaling defect in human and mouse

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Schwerd T. et al, (2020), Bone Research, 8

Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome

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Béziat V. et al, (2020), Journal of Experimental Medicine, 217

Absence of GP130 cytokine receptor signaling causes extended Stüve-Wiedemann syndrome

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Chen Y-H. et al, (2020), Journal of Experimental Medicine, 217

Publisher Correction: An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells

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Aschenbrenner D. et al, (2019), Nature Immunology, 20, 109 - 109

A biallelic mutation in IL6ST encoding the GP130 coreceptor causes immunodeficiency and craniosynostosis

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Schwerd T. et al, (2017), Journal of Experimental Medicine

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

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Zielinski CE. et al, (2012), Nature, 484, 514 - 518