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In a double-blind cross-over trial of disodium cromoglycate on 11 patients nine were symptomatically improved, and in all of these daily measurements of peak expiratory flow increased. The forced expiratory volume in the first second and specific airway conductance did not increase in all patients. In most cases the average values for residual volume and functional residual capacity fell; exercise capacity and ventilation did not change, but the pulse rate on exercise was lower. It is suggested that the changes produced by disodium cromoglycate are worth while.


Journal article


Br Med J

Publication Date





552 - 554


Adolescent, Adrenal Cortex Hormones, Adult, Asthma, Atropine, Chromones, Clinical Trials as Topic, Female, Humans, Male, Middle Aged, Physical Exertion, Pulse, Respiratory Function Tests, Spirometry