Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas
Heino S., Fang S., Lähde M., Högström J., Nassiri S., Campbell A., Flanagan D., Raven A., Hodder M., Nasreddin N., Xue H-H., Delorenzi M., Leedham S., Petrova TV., Sansom O., Alitalo K.
Lef1 is induced in intestinal adenomas, in which it restricts ectopic crypt formation and tumor growth.