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HPRU PUBLICATIONS

2025 

  • Interplay between C-reactive protein responses and antibiotic prescribing in people with suspected infection. GuQ, Yuan K, Wei J, Yoon CH, Danielsen AS, Luk A, et al. 

https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-025-11381-9

  • Case ascertainment of a potential centrally-implemented, automated system for national surveillance of healthcare-associated infections, England, 2016 to 2023.  Cregan J, Nsonwu O. Chudasama D, Hopkins S, Muller-Pebody B, Hope R, et al. 

https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.42.2500066

  • Escherichia coli phylogeny drives co-amoxiclav resistance through variable expression of TEM-1 beta-lactamase. Matlock W, Rodger G, Pritchard E, Colpus M, Kapel N, Barrett L, et al. 

https://www.nature.com/articles/s41467-025-63714-6

  • The impact of inter-infection time on antimicrobial resistance profiles in women with multiple urinary tract infections over time. Honda T, Vazquez-Montes MDLA, Fanshawe TR, Stoesser N, Butler CC, Walker AS, et al. 

https://pubmed.ncbi.nlm.nih.gov/40581812/

  • Estimating the effect of antimicrobial resistance genes on minimum inhibitory concentration in Escherichia coli. Lipworth S, Chau K, Oakley S, Barrett Lucinda, Crrok Derrick, Peto T, et al. 

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00111-9/fulltext

  • Evaluating 12 automated, whole-genome sequencing analysis pipelines for Mycobacterium tuberculosis complex: a comparative study. Spies R, Crook DW, Peto TEA, Fowler PW, Turner R, Thai H, et al. 

         https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00138-7/fulltext

  • Rapid, accurate, and reproducible de novo prediction of resistance to antituberculars. Zhang X, Wan S, Bhati AP, Fowler PW, Coveney PV. 

        https://journals.asm.org/doi/10.1128/msphere.00571-25

  • An improved catalogue for whole-genome sequencing prediction of bedaquiline resistance in M. tuberculosis using a reproducible algorithmic approach. Adhlard D, Joseph L, Webster H, O'Reilly A, Knaggs J, Peto TEA, et al. 

         https://www.microbiologyresearch.org/content/journal/mgen/10.1099/mgen.0.001429

  • An electronic health record-wide association study to identify populations at increased risk of E. coli bacteraemia. Pritchard E, Vihta K, Lipworth S, Pouwels KB, Stoesser N, Hope R, et al. 

        https://www.sciencedirect.com/science/article/pii/S0163445325002129

  • Subpopulations in clinical samples of M. tuberculosis can give rise to rifampicin resistance and shed light on how resistance is acquired. Brunner V, Fowler P. 

         https://academic.oup.com/jacamr/article/7/5/dlaf175/8279675?login=false

  • Dissemination of OXA-23 carbapenemase in Proteus mirabilis and Escherichia coli driven by transposon-carrying lineages. Zamudio R, Osman K, Pike R, Chaudhry A, Meunier D, Stoesser N, et al. 

         https://www.microbiologyresearch.org/content/journal/mgen/10.1099/mgen.0.001502

  • Stop antibiotics when you feel better? Opportunities, challenges and research directions. Borek AJ, Ledda A, Pouwels KB, Butler CC, Hayward G, Walker AS et al. 

         https://academic.oup.com/jacamr/article/6/5/dlae147/7753463

  • Timeliness of a potential automated system for national surveillance of healthcare-associated infections in England. Quan TP, Eyre D, Shadwell S, West D, Hopkins S, Chudasama D, et al. 
    https://pubmed.ncbi.nlm.nih.gov/40288583/
  • General practice antibiotic prescriptions attributable to respiratory syncytial virus by age and antibiotic class: an ecological analysis of the English population. Miller L, Beaney T, Hope R, Cunningham M, Robotham J, Powels K, et al. 
    https://academic.oup.com/jac/article/80/4/1116/8023879
  • Rapid antibiotic susceptibility testing for urinary tract infections in secondary care in England: a cost-effectiveness analysis. Booton RD, Agnew E, Pople D, Evans S, Bock LJ, Sutton MJ, et al. 
    https://bmjopen.bmj.com/content/14/11/e081865