Search results (35)
« Back to PublicationsEpithelial GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche through stromal remodelling
Journal article
Mulholland EJ. et al, (2025), Nature Communications, 16
Molecular mechanism of BMP signal control by Twisted gastrulation
Journal article
Malinauskas T. et al, (2024), Nature Communications, 15
Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis
Journal article
Brown M. et al, (2023), EMBO Molecular Medicine, 15
Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features
Journal article
Flanagan DJ. et al, (2023), Nature Communications, 14
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features
Journal article
Flanagan DJ. et al, (2022), Nature Communications, 13
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Journal article
Vasquez EG. et al, (2022), Cell stem cell, 29, 1213 - 1228.e8
Molecular phenotyping of colorectal neoplasia shows dynamic and adaptive cancer stem cell population admixture
Preprint
Vazquez EG. et al, (2022)
Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration
Journal article
Koppens MAJ. et al, (2021), Gastroenterology, 161, 239 - 254.e9
BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration
Preprint
Koppens MAJ. et al, (2021)
Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification
Journal article
Kleeman SO. et al, (2020), Gut, 69, 1092 - 1103
Negative selection may cause grossly altered but broadly stable karyotypes in metastatic colorectal cancer
Preprint
Cross W. et al, (2020)
The polymorphic variant rs1800734 influences methylation acquisition and allele-specific TFAP4 binding in the MLH1 promoter leading to differential mRNA expression.
Journal article
Thomas R. et al, (2019), Scientific reports, 9
Evolutionary history of human colitis-associated colorectal cancer
Journal article
Baker A-M. et al, (2019), Gut, 68, 985 - 995
The evolutionary landscape of colorectal tumorigenesis
Journal article
Cross W. et al, (2018), Nature Ecology & Evolution, 2, 1661 - 1672
Bone morphogenetic protein and Notch signalling crosstalk in poor‐prognosis, mesenchymal‐subtype colorectal cancer
Journal article
Irshad S. et al, (2017), The Journal of Pathology, 242, 178 - 192
