Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018.

Eyre DW., Town K., Street T., Barker L., Sanderson N., Cole MJ., Mohammed H., Pitt R., Gobin M., Irish C., Gardiner D., Sedgwick J., Beck C., Saunders J., Turbitt D., Cook C., Phin N., Nathan B., Horner P., Fifer H.

We describe detection in the United Kingdom (UK) of the drug-resistant Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate azithromycin resistance. Two female patients developed infection following contact with UK-resident men from the same sexual network linked to travel to Ibiza, Spain. One case failed treatment with ceftriaxone, and azithromycin and gentamicin, before successful treatment with ertapenem. Both isolates had indistinguishable whole-genome sequences. Urgent action is essential to contain this drug-resistant strain.

DOI

10.2807/1560-7917.es.2019.24.10.1900147

Type

Journal article

Journal

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Publication Date

07/03/2019

Volume

24

Addresses

Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

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