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Three cases of severe and irreversible alopecia occurring in patients with common variable immunodeficiency are described. In all three cases, hair loss developed after the diagnosis of immune deficiency; one of the patients also had extensive vitiligo. A fourth patient had vitiligo in the absence of alopecia. No change in the alopecia or vitiligo was noted in any patient as a result of immunoglobulin replacement therapy.


Journal article


Postgrad Med J

Publication Date





291 - 294


Adult, Alopecia, Humans, Immunization, Passive, Immunologic Deficiency Syndromes, Male, Middle Aged, Vitiligo