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The activity of atovaquone in patients with oligosymptomatic Plasmodium falciparum malaria was assessed in an open, non-comparative clinical study. The patients showed a good clinical response, but there was a high rate of recrudescence. The activity of atovaquone in combination with another antimalarial agent should be investigated.


Journal article


J Antimicrob Chemother

Publication Date





1073 - 1078


Adult, Antimalarials, Atovaquone, Dose-Response Relationship, Drug, Drug Administration Schedule, Evaluation Studies as Topic, Humans, Malaria, Falciparum, Male, Middle Aged, Naphthoquinones, Treatment Outcome