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The authors present the cases of two patients with carcinoma of the gallbladder complicating chronic ulcerative colitis. Both patients had concomitant primary sclerosing cholangitis. Twelve such cases of gallbladder carcinoma have been reported in the literature. The presence of primary sclerosing cholangitis in patients with ulcerative colitis is associated with malignancy of the extrahepatic biliary tree. It is suggested that, if colectomy is necessary, the liver should be biopsied and a cholecystectomy performed if the gallbladder is deemed abnormal.


Journal article


Dis Colon Rectum

Publication Date





827 - 828


Aged, Biopsy, Carcinoma, Cholangitis, Sclerosing, Cholecystectomy, Colectomy, Colitis, Ulcerative, Female, Gallbladder Neoplasms, Humans, Male, Middle Aged