Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences
Martinez FO., Helming L., Milde R., Varin A., Melgert BN., Draijer C., Thomas B., Fabbri M., Crawshaw A., Ho LP., Ten Hacken NH., Cobos Jiménez V., Kootstra NA., Hamann J., Greaves DR., Locati M., Mantovani A., Gordon S.
Key PointsHuman and mouse macrophages share partially conserved gene and protein expression programs in the resting or M2 activated state. TGM2 is a novel M2 marker consistently induced in human and mouse M2 macrophages.