Oxford Respiratory Trials Unit (ORTU)
About ORTU
The Oxford Respiratory Trials Unit (ORTU) is a Clinical Trials Unit which specialises in the design, delivery and administration of trials across the scope of Respiratory Medicine.
We run national and international trials related to our own academic areas, as well as supporting trials led by other teams. Our scope of work includes clinical trials at all phases, including translational studies, phase II discovery studies and multicentre definitive randomised trials.
We partner with a broad range of academic funders (National Institute of Health Research, Medical Research Council, British Lung Foundation, National Cancer Research Institute, CRUK) and partners in industry. Key funding for ORTU is derived from the Comprehensive Local Research Network (CLRN) and the Oxford NIHR Biomedical Research Centre.
ORTU publications
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Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity.
Journal article
Hamid MHBA. et al, (2024), Nat Immunol
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Lung Ultrasound Reproducibly Outperforms Computed Tomography in the Detection of Extravascular Lung Water in Patients Undergoing Haemodialysis
Journal article
Corcoran JP. et al, (2024), Diagnostics, 14, 589 - 589
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Development and evaluation of a tool to optimise inhaler selection prior to hospital discharge following an exacerbation of COPD.
Journal article
Price E. et al, (2024), ERJ open research, 10, 10 - 2024
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Pleural Diseases in Connective Tissue Diseases.
Journal article
Guo H. et al, (2024), Seminars in respiratory and critical care medicine
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The lung is not a balloon: the self-sealing property of the lung.
Journal article
Chopra A. et al, (2024), The Lancet. Respiratory medicine, 12, 190 - 192
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Reply to: Insights on the ERS/ESTS statement on the management of pleural infection in adults.
Journal article
Bedawi EO. and Rahman NM., (2024), The European respiratory journal, 63
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Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients
Journal article
Standing JF. et al, (2024), Nature Communications, 15
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Man versus Machine in Pleural Diagnostics: Does Artificial Intelligence Provide the Solution?
Journal article
Addala DN. and Rahman NM., (2024), Annals of the American Thoracic Society, 21, 202 - 203